Linked Life Data

21595265

Source:http://linkedlifedata.com/resource/pubmed/id/21595265

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2011-5-19
pubmed:abstractText
Incretins including GLP-1 and GIP have pleiotropic effects on islet biology especially on beta-cell function. Not only enhancing glucose-stimulated insulin secretion, but incretins exert beta-cell mass maintaining effects by upregulation of proliferation and prevention of cell death (apoptosis). Recent research data revealed detailed molecular mechanisms underlying these effects of incretin on beta-cell biology. These beneficial effects of incretins on the regulation of beta-cell mass could contribute to future therapeutic approaches to diabetes focusing on preservation and upregulation of beta-cell mass as well as function.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0047-1852
pubmed:author
pubmed:issnType
Print
pubmed:volume
69
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
821-5
pubmed:dateRevised
2011-7-27
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
[Effects of incretins on the regulation of beta-cell mass, proliferation and survival].
pubmed:affiliation
Department of Metabolic Medicine, Osaka University Graduate School of Medicine.
pubmed:publicationType
Journal Article, English Abstract