| pubmed-article:2158905 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2158905 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:2158905 | lifeskim:mentions | umls-concept:C0026473 | lld:lifeskim |
| pubmed-article:2158905 | lifeskim:mentions | umls-concept:C0001455 | lld:lifeskim |
| pubmed-article:2158905 | lifeskim:mentions | umls-concept:C1819435 | lld:lifeskim |
| pubmed-article:2158905 | lifeskim:mentions | umls-concept:C1709059 | lld:lifeskim |
| pubmed-article:2158905 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:2158905 | pubmed:dateCreated | 1990-6-6 | lld:pubmed |
| pubmed-article:2158905 | pubmed:abstractText | Elevation of cAMP has been considered to be an important downregulative signal in the production of interleukin-1(IL-1). This study demonstrates that this phenomenon is dependent on the signal used to activate the IL-1 production. The IL-1 beta production of lipopolysaccharide activated human monocytes was readily inhibited by dibutyryl cAMP. This took place without a significant change in the steady-state levels of IL-1 beta mRNA. By contrast, in PMA activated monocytes 100 microM dibutyryl cAMP increased in IL-1 beta production ca. 4-fold. The steady-state levels of IL-1 beta mRNA were also simultaneously increased. | lld:pubmed |
| pubmed-article:2158905 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2158905 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2158905 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2158905 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2158905 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2158905 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2158905 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2158905 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2158905 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2158905 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2158905 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2158905 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:2158905 | pubmed:issn | 0014-5793 | lld:pubmed |
| pubmed-article:2158905 | pubmed:author | pubmed-author:HurmeMM | lld:pubmed |
| pubmed-article:2158905 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2158905 | pubmed:day | 9 | lld:pubmed |
| pubmed-article:2158905 | pubmed:volume | 263 | lld:pubmed |
| pubmed-article:2158905 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2158905 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2158905 | pubmed:pagination | 35-7 | lld:pubmed |
| pubmed-article:2158905 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2158905 | pubmed:meshHeading | pubmed-meshheading:2158905-... | lld:pubmed |
| pubmed-article:2158905 | pubmed:meshHeading | pubmed-meshheading:2158905-... | lld:pubmed |
| pubmed-article:2158905 | pubmed:meshHeading | pubmed-meshheading:2158905-... | lld:pubmed |
| pubmed-article:2158905 | pubmed:meshHeading | pubmed-meshheading:2158905-... | lld:pubmed |
| pubmed-article:2158905 | pubmed:meshHeading | pubmed-meshheading:2158905-... | lld:pubmed |
| pubmed-article:2158905 | pubmed:meshHeading | pubmed-meshheading:2158905-... | lld:pubmed |
| pubmed-article:2158905 | pubmed:meshHeading | pubmed-meshheading:2158905-... | lld:pubmed |
| pubmed-article:2158905 | pubmed:meshHeading | pubmed-meshheading:2158905-... | lld:pubmed |
| pubmed-article:2158905 | pubmed:meshHeading | pubmed-meshheading:2158905-... | lld:pubmed |
| pubmed-article:2158905 | pubmed:meshHeading | pubmed-meshheading:2158905-... | lld:pubmed |
| pubmed-article:2158905 | pubmed:meshHeading | pubmed-meshheading:2158905-... | lld:pubmed |
| pubmed-article:2158905 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2158905 | pubmed:articleTitle | Modulation of interleukin-1 beta production by cyclic AMP in human monocytes. | lld:pubmed |
| pubmed-article:2158905 | pubmed:affiliation | Department of Bacteriology and Immunology, University of Helsinki, Finland. | lld:pubmed |
| pubmed-article:2158905 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2158905 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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