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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2011-5-18
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pubmed:abstractText |
We investigated the immunostimulatory effects of a novel ?-glucan purified from Paenibacillus (P.) polymyxa JB115 on bone marrow-derived dendritic cells (DCs), a type of potent antigen-presenting cells. ?-glucan isolated from P. polymyxa JB115 enhanced the viability and induced the maturation of DCs. ?-glucan markedly increased the cytokine production of DCs and surface expression of DC markers. In addition, DCs treated with ?-glucan showed a higher capacity to stimulate allogeneic spleen cell proliferation compared to those treated with medium alone. These results demonstrate the effect of ?-glucan on DC maturation and may increase the use of ?-glucan.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/21586879-11300499,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21586879-11310841,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21586879-11509172,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21586879-15760447,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21586879-18077003,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21586879-19594628,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21586879-19885033,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21586879-20026063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21586879-7514631,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21586879-7525841,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21586879-8605935,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21586879-9176697
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1976-555X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
187-9
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pubmed:meshHeading |
pubmed-meshheading:21586879-Animals,
pubmed-meshheading:21586879-Bone Marrow Cells,
pubmed-meshheading:21586879-Cell Survival,
pubmed-meshheading:21586879-Dendritic Cells,
pubmed-meshheading:21586879-Flow Cytometry,
pubmed-meshheading:21586879-Immunophenotyping,
pubmed-meshheading:21586879-Interleukin-12,
pubmed-meshheading:21586879-Mice,
pubmed-meshheading:21586879-Mice, Inbred BALB C,
pubmed-meshheading:21586879-Nitric Oxide,
pubmed-meshheading:21586879-Paenibacillus,
pubmed-meshheading:21586879-Tumor Necrosis Factor-alpha,
pubmed-meshheading:21586879-beta-Glucans
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pubmed:year |
2011
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pubmed:articleTitle |
Maturation of bone marrow-derived dendritic cells by a novel ?-glucan purified from Paenibacillus polymyxa JB115.
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pubmed:affiliation |
College of Veterinary Medicine, Jeju National University, Jeju 690-756, Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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