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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1990-5-24
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pubmed:abstractText |
Five DNA-binding sites for the Epstein-Barr virus BZLF1 protein have been identified within three of the early viral promoters, and four of these binding sites contain a consensus AP-1 site. The part of the BZLF1 protein required for sequence-specific DNA binding to one of these AP-1-like sites was identified by deletion mapping. Site-directed mutagenesis of this DNA target suggests that BZLF1 may work partly by overcoming a cellular repressor of viral transcription.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-2462063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-2498162,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-2498806,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-2538653,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-2540954,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-2542612,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-2542618,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-2548002,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-2548003,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-2548844,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-2824806,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-2836611,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-2987963,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-3005608,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-3018281,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-3028777,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-3041034,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-3041051,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-3881765,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2157874-6087149
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2110-6
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:2157874-Amino Acid Sequence,
pubmed-meshheading:2157874-Animals,
pubmed-meshheading:2157874-Base Sequence,
pubmed-meshheading:2157874-Cell Line,
pubmed-meshheading:2157874-Chromosome Deletion,
pubmed-meshheading:2157874-DNA-Binding Proteins,
pubmed-meshheading:2157874-Genes, Viral,
pubmed-meshheading:2157874-Herpesvirus 4, Human,
pubmed-meshheading:2157874-Molecular Sequence Data,
pubmed-meshheading:2157874-Mutation,
pubmed-meshheading:2157874-Nucleotide Mapping,
pubmed-meshheading:2157874-Oligonucleotide Probes,
pubmed-meshheading:2157874-Plasmids,
pubmed-meshheading:2157874-Promoter Regions, Genetic,
pubmed-meshheading:2157874-Protein Biosynthesis,
pubmed-meshheading:2157874-Restriction Mapping,
pubmed-meshheading:2157874-Sequence Homology, Nucleic Acid,
pubmed-meshheading:2157874-Trans-Activators,
pubmed-meshheading:2157874-Transcription, Genetic,
pubmed-meshheading:2157874-Transfection,
pubmed-meshheading:2157874-Viral Proteins
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pubmed:year |
1990
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pubmed:articleTitle |
Structure and function of the Epstein-Barr virus BZLF1 protein.
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pubmed:affiliation |
Ludwig Institute for Cancer Research, St. Mary's Hospital Medical School, London, England.
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pubmed:publicationType |
Journal Article,
Comparative Study
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