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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1990-5-24
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pubmed:abstractText |
Pilocarpine-induced saliva of adult female Ixodes dammini ticks inhibits the function of peritoneal-derived rat neutrophils, as measured by anaphylatoxin-induced aggregation, FMLP-induced granule enzyme secretion, zymosan-induced superoxide secretion, and phagocytosis of Borrelia burgdorferi spirochetes. Inhibition ranged from 40 to 80% when saliva was diluted 20 times into the assay medium. This neutrophil-inhibiting activity of I. dammini saliva may aid in tick feeding and facilitate pathogen transmission.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
|
pubmed:issn |
0014-4894
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
70
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
382-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2157607-Animals,
pubmed-meshheading:2157607-Borrelia burgdorferi Group,
pubmed-meshheading:2157607-Cell Aggregation,
pubmed-meshheading:2157607-Cell Survival,
pubmed-meshheading:2157607-Female,
pubmed-meshheading:2157607-Glucuronidase,
pubmed-meshheading:2157607-Male,
pubmed-meshheading:2157607-Neutrophils,
pubmed-meshheading:2157607-Phagocytosis,
pubmed-meshheading:2157607-Rats,
pubmed-meshheading:2157607-Rats, Inbred Strains,
pubmed-meshheading:2157607-Saliva,
pubmed-meshheading:2157607-Superoxides,
pubmed-meshheading:2157607-Ticks
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pubmed:year |
1990
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pubmed:articleTitle |
Saliva of the tick Ixodes dammini inhibits neutrophil function.
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pubmed:affiliation |
Harvard School of Public Health, Department of Tropical Public Health, Boston, Massachusetts 02115.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|