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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1990-5-24
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pubmed:abstractText |
Exposure to nitrous oxide produced concentration-dependent analgesia in the mouse abdominal constriction test. Intracerebroventricular or intrathecal pretreatment with naltrexone or nor-binaltorphimine significantly reduced nitrous oxide analgesia. However, similar pretreatment with beta-funaltrexamine had no appreciable effect. These findings suggest that nitrous oxide analgesia involves spinal and supraspinal kappa-opioid receptors.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0014-2999
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
3
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pubmed:volume |
175
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
97-100
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2157601-Analgesics,
pubmed-meshheading:2157601-Animals,
pubmed-meshheading:2157601-Dose-Response Relationship, Drug,
pubmed-meshheading:2157601-Injections, Intraventricular,
pubmed-meshheading:2157601-Injections, Spinal,
pubmed-meshheading:2157601-Male,
pubmed-meshheading:2157601-Mice,
pubmed-meshheading:2157601-Mice, Inbred ICR,
pubmed-meshheading:2157601-Naltrexone,
pubmed-meshheading:2157601-Nitrous Oxide,
pubmed-meshheading:2157601-Pain Measurement,
pubmed-meshheading:2157601-Receptors, Opioid,
pubmed-meshheading:2157601-Receptors, Opioid, kappa,
pubmed-meshheading:2157601-Spinal Cord
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pubmed:year |
1990
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pubmed:articleTitle |
Mediation of nitrous oxide analgesia in mice by spinal and supraspinal kappa-opioid receptors.
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pubmed:affiliation |
Department of Basic Sciences, Marquette University School of Dentistry, Milwaukee, WI 53233.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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