Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2011-6-27
pubmed:abstractText
We report the first quantitative assessment of DNA methylation for any gene in the human preimplantation embryo to reveal that imprints exist at KvDMR1, RB1, SNRPN, and GRB10 in the human blastocyst. For comparison, in two human embryonic stem cell lines, imprints were also observed at KvDMR1, SNRPN, GRB10, and other imprinted loci, whereas RB1 and MEG3 were hypermethylated.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1556-5653
pubmed:author
pubmed:copyrightInfo
Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
30
pubmed:volume
95
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2564-7.e1-8
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Quantitative analysis of DNA methylation of imprinted genes in single human blastocysts by pyrosequencing.
pubmed:affiliation
Division of Reproduction and Early Development, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, The LIGHT Laboratories, Clarendon Way, Leeds, United Kingdom. j.huntriss@leeds.ac.uk
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't