Transforming growth factor-? 1 (TGF-?1) participates in the synthesis and deposition of collagen. It has been implicated in fibrosis of tendons in wound-healing models but has never been studied in muscles with respect to distraction osteogenesis.
Department of Pathology, University of Wisconsin School of Medicine and Public Health, Highland Avenue, Madison, WI 53215, USA. stephanie.koplin@aurora.org