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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2011-9-6
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pubmed:abstractText |
Hepatic macrophages (Kupffer cells) undergo inflammatory activation during the development of portal hypertension in experimental cirrhosis; this activation may play a pathogenic role or be an epiphenomenon. Our objective was to study serum soluble CD163 (sCD163), a sensitive marker of macrophage activation, before and after reduction of portal venous pressure gradient by insertion of a transjugular intrahepatic portosystemic shunt (TIPS) in patients with cirrhosis.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1468-3288
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1389-93
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:21572121-Adult,
pubmed-meshheading:21572121-Aged,
pubmed-meshheading:21572121-Antigens, CD,
pubmed-meshheading:21572121-Antigens, CD63,
pubmed-meshheading:21572121-Female,
pubmed-meshheading:21572121-Humans,
pubmed-meshheading:21572121-Hypertension, Portal,
pubmed-meshheading:21572121-Immunity, Cellular,
pubmed-meshheading:21572121-Kupffer Cells,
pubmed-meshheading:21572121-Liver Cirrhosis,
pubmed-meshheading:21572121-Macrophage Activation,
pubmed-meshheading:21572121-Male,
pubmed-meshheading:21572121-Middle Aged,
pubmed-meshheading:21572121-Platelet Membrane Glycoproteins,
pubmed-meshheading:21572121-Portal Pressure,
pubmed-meshheading:21572121-Portasystemic Shunt, Transjugular Intrahepatic,
pubmed-meshheading:21572121-Prognosis,
pubmed-meshheading:21572121-Recovery of Function
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pubmed:year |
2011
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pubmed:articleTitle |
Kupffer cells are activated in cirrhotic portal hypertension and not normalised by TIPS.
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pubmed:affiliation |
Department of Medicine V (Hepato and Gastroenterology), Aarhus University Hospital, Aarhus, Denmark. phf@svf.au.dk
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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