| pubmed-article:2157158 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2157158 | lifeskim:mentions | umls-concept:C0006675 | lld:lifeskim |
| pubmed-article:2157158 | lifeskim:mentions | umls-concept:C0042567 | lld:lifeskim |
| pubmed-article:2157158 | lifeskim:mentions | umls-concept:C0027747 | lld:lifeskim |
| pubmed-article:2157158 | lifeskim:mentions | umls-concept:C0015283 | lld:lifeskim |
| pubmed-article:2157158 | lifeskim:mentions | umls-concept:C0242485 | lld:lifeskim |
| pubmed-article:2157158 | lifeskim:mentions | umls-concept:C0439851 | lld:lifeskim |
| pubmed-article:2157158 | lifeskim:mentions | umls-concept:C1552596 | lld:lifeskim |
| pubmed-article:2157158 | lifeskim:mentions | umls-concept:C0205171 | lld:lifeskim |
| pubmed-article:2157158 | lifeskim:mentions | umls-concept:C0521116 | lld:lifeskim |
| pubmed-article:2157158 | lifeskim:mentions | umls-concept:C1947931 | lld:lifeskim |
| pubmed-article:2157158 | pubmed:issue | 6265 | lld:pubmed |
| pubmed-article:2157158 | pubmed:dateCreated | 1990-5-3 | lld:pubmed |
| pubmed-article:2157158 | pubmed:abstractText | The release of neurohormone is widely thought to be exocytotic, involving Ca2(+)-dependent fusion of secretory vesicles with the plasma membrane. The inaccessibility of most nerve ending has so far hampered direct time-resolved measurements of neuronal exocytosis in response to brief depolarization. By using 'whole-terminal' patch-clamp and circuit-analysis techniques to measure membrane capacitance, we have now monitored changes in the surface membrane area of individual nerve terminals isolated from the mammalian neurohypophysis. A single depolarizing pulse leading to Ca2+ entry through voltage-gated calcium channels, rapidly and reproducibly increases the membrane area by an amount corresponding to the fusion of 1-100 secretory vesicles. The magnitude of the capacitance increase depends not only on Ca2+ entry and buffering, but also on the pattern of stimulation revealing facilitation, fatigue and recovery of the release process. | lld:pubmed |
| pubmed-article:2157158 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2157158 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2157158 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2157158 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2157158 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2157158 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2157158 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2157158 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:2157158 | pubmed:issn | 0028-0836 | lld:pubmed |
| pubmed-article:2157158 | pubmed:author | pubmed-author:NowyckyM CMC | lld:pubmed |
| pubmed-article:2157158 | pubmed:author | pubmed-author:BookmanR JRJ | lld:pubmed |
| pubmed-article:2157158 | pubmed:author | pubmed-author:LinN GNG | lld:pubmed |
| pubmed-article:2157158 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2157158 | pubmed:day | 29 | lld:pubmed |
| pubmed-article:2157158 | pubmed:volume | 344 | lld:pubmed |
| pubmed-article:2157158 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2157158 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2157158 | pubmed:pagination | 449-51 | lld:pubmed |
| pubmed-article:2157158 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2157158 | pubmed:meshHeading | pubmed-meshheading:2157158-... | lld:pubmed |
| pubmed-article:2157158 | pubmed:meshHeading | pubmed-meshheading:2157158-... | lld:pubmed |
| pubmed-article:2157158 | pubmed:meshHeading | pubmed-meshheading:2157158-... | lld:pubmed |
| pubmed-article:2157158 | pubmed:meshHeading | pubmed-meshheading:2157158-... | lld:pubmed |
| pubmed-article:2157158 | pubmed:meshHeading | pubmed-meshheading:2157158-... | lld:pubmed |
| pubmed-article:2157158 | pubmed:meshHeading | pubmed-meshheading:2157158-... | lld:pubmed |
| pubmed-article:2157158 | pubmed:meshHeading | pubmed-meshheading:2157158-... | lld:pubmed |
| pubmed-article:2157158 | pubmed:meshHeading | pubmed-meshheading:2157158-... | lld:pubmed |
| pubmed-article:2157158 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2157158 | pubmed:articleTitle | Direct measurement of exocytosis and calcium currents in single vertebrate nerve terminals. | lld:pubmed |
| pubmed-article:2157158 | pubmed:affiliation | Department of Biochemistry and Biophysics, School of Medicine, University of Pennsylvania, Philadelphia 19104. | lld:pubmed |
| pubmed-article:2157158 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2157158 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2157158 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2157158 | lld:pubmed |
