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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2011-6-7
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pubmed:abstractText |
Restless legs syndrome (RLS) is a neurological disorder characterized by a strong urge to move the legs and has been shown in many studies with abnormally low brain iron. Iron deficiency is associated with hypomyelination in brains of animals. Therefore we hypothesized that a myelin deficit should be present in the brains of patients with RLS.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1878-5506
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2011 Elsevier B.V. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
614-9
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:21570342-Adult,
pubmed-meshheading:21570342-Aged,
pubmed-meshheading:21570342-Apoferritins,
pubmed-meshheading:21570342-Demyelinating Diseases,
pubmed-meshheading:21570342-Female,
pubmed-meshheading:21570342-Frontal Lobe,
pubmed-meshheading:21570342-Humans,
pubmed-meshheading:21570342-Magnetic Resonance Imaging,
pubmed-meshheading:21570342-Male,
pubmed-meshheading:21570342-Middle Aged,
pubmed-meshheading:21570342-Myelin Proteins,
pubmed-meshheading:21570342-Myelin Sheath,
pubmed-meshheading:21570342-Nerve Fibers, Myelinated,
pubmed-meshheading:21570342-Restless Legs Syndrome,
pubmed-meshheading:21570342-Temporal Lobe,
pubmed-meshheading:21570342-Tissue Banks,
pubmed-meshheading:21570342-Transferrin
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pubmed:year |
2011
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pubmed:articleTitle |
Postmortem and imaging based analyses reveal CNS decreased myelination in restless legs syndrome.
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pubmed:affiliation |
Department of Neurosurgery, Pennsylvania State University College of Medicine, Milton S. Hershey Medical Center, Hershey, PA 17033-0850, USA. jconnor@hmc.psu.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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