rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2011-6-13
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pubmed:abstractText |
Environmental stress plays an important role in the development of glucose intolerance influencing lipid and glucose metabolism through sympathetic nervous system, cytokines and hormones such as glucocorticoids, catecholamines and glucagon. Otherwise, fish oil prevents glucose intolerance and insulin resistance. Although the mechanisms involved are not fully understood, it is known that sympathetic and HPA responses are blunted and catecholamines and glucocorticoids concentrations can be modulated by fish consumption. The aim of the present study was to evaluate whether fish oil, on a normal lipidic diet: 1) could prevent the effect of footshock-stress on the development of glucose intolerance; 2) modified adiponectin receptor and serum concentration; and 3) also modified TNF-?, IL-6 and interleukin-10 (IL-10) levels in adipose tissue and liver. The study was performed in thirty day-old male Wistar randomly assigned into four groups: no stressed (C) and stressed (CS) rats fed with control diet, and no stressed (F) and stressed (FS) rats fed with a fish oil rich diet. The stress was performed as a three daily footshock stress sessions.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adiponectin,
http://linkedlifedata.com/resource/pubmed/chemical/Blood Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Corticosterone,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/Fish Oils,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Adiponectin,
http://linkedlifedata.com/resource/pubmed/chemical/adiponectin receptor 1, rat,
http://linkedlifedata.com/resource/pubmed/chemical/adiponectin receptor 2, rat
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pubmed:status |
MEDLINE
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pubmed:issn |
1476-511X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
71
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:21569357-Adiponectin,
pubmed-meshheading:21569357-Animals,
pubmed-meshheading:21569357-Area Under Curve,
pubmed-meshheading:21569357-Blood Glucose,
pubmed-meshheading:21569357-Body Composition,
pubmed-meshheading:21569357-Corticosterone,
pubmed-meshheading:21569357-Cytokines,
pubmed-meshheading:21569357-Electroshock,
pubmed-meshheading:21569357-Feeding Behavior,
pubmed-meshheading:21569357-Fish Oils,
pubmed-meshheading:21569357-Glucose Intolerance,
pubmed-meshheading:21569357-Insulin,
pubmed-meshheading:21569357-Male,
pubmed-meshheading:21569357-Organ Specificity,
pubmed-meshheading:21569357-Rats,
pubmed-meshheading:21569357-Rats, Wistar,
pubmed-meshheading:21569357-Receptors, Adiponectin,
pubmed-meshheading:21569357-Stress, Physiological
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pubmed:year |
2011
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pubmed:articleTitle |
Fish oil consumption prevents glucose intolerance and hypercorticosteronemy in footshock-stressed rats.
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pubmed:affiliation |
Departamento de Fisiologia, Universidade de São Paulo - UNIFESP - Rua Botucatu, 862, 2nd floor, Edifício de Ciências Biomédicas, Vila Clementino, São Paulo, SP, Brazil.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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