21566260

Source:http://linkedlifedata.com/resource/pubmed/id/21566260

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0001811, umls-concept:C0205314, umls-concept:C0449445, umls-concept:C0679622, umls-concept:C1423062, umls-concept:C1538577, umls-concept:C2346501
pubmed:issue	5
pubmed:dateCreated	2011-6-13
pubmed:abstractText	Poly(ADP-ribosyl) polymerases (PARPs) have traditionally been linked to chromosome maintenance and DNA repair. Recent findings identify PARPs as key modulators of metabolism through their influence on SIRT1 activity, hinting to a possible role of PARPs as longevity regulators.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/DK59820
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-10331645, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-10364231, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-10809662, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-11053660, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-12297502, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-12673357, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-12727891, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-14019961, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-1465394, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-15744310, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-15855315, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-16497723, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-16628003, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-16804088, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-17595514, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-18392653, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-18662766, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-19713122, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-19751409, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-20007326, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-20045739, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-20338998, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-20561897, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-20603072, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-21307849, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-21459329, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-21459330, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-6458707, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-7698643, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-9207086, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-9587069, http://linkedlifedata.com/resource/pubmed/commentcorrection/21566260-9804757
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101508617
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Poly(ADP-ribose) Polymerases, http://linkedlifedata.com/resource/pubmed/chemical/SIRT1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Sirtuin 1
pubmed:status	MEDLINE
pubmed:month	May
pubmed:issn	1945-4589
pubmed:author	pubmed-author:AuwerxJohanJ, pubmed-author:CantóCarlesC
pubmed:issnType	Electronic
pubmed:volume	3
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	543-7
pubmed:meshHeading	pubmed-meshheading:21566260-Aging, pubmed-meshheading:21566260-Animals, pubmed-meshheading:21566260-Energy Metabolism, pubmed-meshheading:21566260-Humans, pubmed-meshheading:21566260-Mitochondria, pubmed-meshheading:21566260-Poly(ADP-ribose) Polymerases, pubmed-meshheading:21566260-Sirtuin 1
pubmed:year	2011
pubmed:articleTitle	Interference between PARPs and SIRT1: a novel approach to healthy ageing?
pubmed:affiliation	Ecole Polytechnique Fédérale de Lausanne, Switzerland.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural