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rdf:type |
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lifeskim:mentions |
umls-concept:C0007131,
umls-concept:C0017262,
umls-concept:C0078058,
umls-concept:C0185117,
umls-concept:C0851285,
umls-concept:C0964836,
umls-concept:C1149230,
umls-concept:C1256770,
umls-concept:C1416389,
umls-concept:C1416403,
umls-concept:C2911684
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pubmed:issue |
12
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pubmed:dateCreated |
2011-8-8
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pubmed:abstractText |
IL-20 is a pleiotrophic member of the IL-10 family and plays a role in skin biology and the development of haematopoietic cells. Recently, IL-20 has been demonstrated to have potential anti-angiogenic effects in non-small cell lung cancer (NSCLC) by down regulating COX-2.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Angiogenesis Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Histones,
http://linkedlifedata.com/resource/pubmed/chemical/Immunophilins,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor...,
http://linkedlifedata.com/resource/pubmed/chemical/interleukin 20,
http://linkedlifedata.com/resource/pubmed/chemical/interleukin-20 receptor,
http://linkedlifedata.com/resource/pubmed/chemical/interleukin-22 receptor
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1879-0852
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2011 Elsevier Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1908-18
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pubmed:meshHeading |
pubmed-meshheading:21565488-Acetylation,
pubmed-meshheading:21565488-Angiogenesis Inhibitors,
pubmed-meshheading:21565488-Blotting, Western,
pubmed-meshheading:21565488-Bronchi,
pubmed-meshheading:21565488-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:21565488-Cell Line, Tumor,
pubmed-meshheading:21565488-Cell Proliferation,
pubmed-meshheading:21565488-Chromatin Immunoprecipitation,
pubmed-meshheading:21565488-CpG Islands,
pubmed-meshheading:21565488-DNA Methylation,
pubmed-meshheading:21565488-Down-Regulation,
pubmed-meshheading:21565488-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:21565488-Epigenesis, Genetic,
pubmed-meshheading:21565488-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:21565488-Histones,
pubmed-meshheading:21565488-Humans,
pubmed-meshheading:21565488-Immunophilins,
pubmed-meshheading:21565488-Interleukins,
pubmed-meshheading:21565488-Lung Neoplasms,
pubmed-meshheading:21565488-Neovascularization, Pathologic,
pubmed-meshheading:21565488-RNA, Messenger,
pubmed-meshheading:21565488-Receptors, Interleukin,
pubmed-meshheading:21565488-Respiratory Mucosa,
pubmed-meshheading:21565488-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:21565488-Vascular Endothelial Growth Factor A,
pubmed-meshheading:21565488-Vascular Endothelial Growth Factor Receptor-2
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pubmed:year |
2011
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pubmed:articleTitle |
IL-20 is epigenetically regulated in NSCLC and down regulates the expression of VEGF.
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pubmed:affiliation |
Thoracic Oncology Research Group, Institute of Molecular Medicine, Trinity College Dublin, Ireland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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