Source:http://linkedlifedata.com/resource/pubmed/id/21558047
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2011-6-20
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pubmed:abstractText |
USA300 methicillin-resistant Staphylococcus aureus (MRSA) is increasing as a cause of severe community-associated bacteremic infections. We assessed severe sepsis in response to infection in patients with USA300 MRSA compared to non-USA300 MRSA bacteremia. A cohort study was conducted from 1997 to 2008 comparing sepsis in response to infection in 271 patients with MRSA bacteremia from 4 VA hospitals. Sixty-seven (25%) patients with MRSA bacteremia were USA300 MRSA; 204 (75%) were non-USA300 MRSA. The proportion of MRSA bacteremia caused by USA300 MRSA increased over time (?² P < 0.0001). Adjusting for age and nosocomial infection, patients with USA300 MRSA bacteremia were more likely to have severe sepsis or septic shock in response to infection than patients with non-USA300 MRSA bacteremia (adjusted relative risk = 1.82; 95% confidence interval, 1.16-2.87; P = 0.01). This suggests that patients with USA300 MRSA are more likely to develop severe sepsis in response to their infection, which could be due to host or bacterial differences.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1879-0070
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2011 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
70
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
285-90
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pubmed:meshHeading |
pubmed-meshheading:21558047-Aged,
pubmed-meshheading:21558047-Aged, 80 and over,
pubmed-meshheading:21558047-Bacterial Typing Techniques,
pubmed-meshheading:21558047-Cohort Studies,
pubmed-meshheading:21558047-Female,
pubmed-meshheading:21558047-Genotype,
pubmed-meshheading:21558047-Humans,
pubmed-meshheading:21558047-Incidence,
pubmed-meshheading:21558047-Male,
pubmed-meshheading:21558047-Methicillin-Resistant Staphylococcus aureus,
pubmed-meshheading:21558047-Middle Aged,
pubmed-meshheading:21558047-Prevalence,
pubmed-meshheading:21558047-Risk Factors,
pubmed-meshheading:21558047-Sepsis,
pubmed-meshheading:21558047-Staphylococcal Infections,
pubmed-meshheading:21558047-United States
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pubmed:year |
2011
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pubmed:articleTitle |
USA300 methicillin-resistant Staphylococcus aureus bacteremia and the risk of severe sepsis: is USA300 methicillin-resistant Staphylococcus aureus associated with more severe infections?
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pubmed:affiliation |
University of Maryland Baltimore, Baltimore, MD 21201, USA. kris03222001@yahoo.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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