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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2011-5-10
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pubmed:abstractText |
The main determinants of HIV-1 coreceptor usage are located in the V3-loop of gp120, although mutations in V2 and gp41 are also known. Incorporation of V2 is known to improve prediction algorithms; however, this has not been confirmed for gp41 mutations.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-HIV Agents,
http://linkedlifedata.com/resource/pubmed/chemical/CXCR4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclohexanes,
http://linkedlifedata.com/resource/pubmed/chemical/HIV Envelope Protein gp41,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CCR5,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CXCR4,
http://linkedlifedata.com/resource/pubmed/chemical/Reverse Transcriptase Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Triazoles,
http://linkedlifedata.com/resource/pubmed/chemical/maraviroc
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pubmed:status |
MEDLINE
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pubmed:issn |
2040-2058
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
319-28
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pubmed:meshHeading |
pubmed-meshheading:21555814-Algorithms,
pubmed-meshheading:21555814-Amino Acid Sequence,
pubmed-meshheading:21555814-Anti-HIV Agents,
pubmed-meshheading:21555814-Cyclohexanes,
pubmed-meshheading:21555814-HIV Envelope Protein gp41,
pubmed-meshheading:21555814-HIV Infections,
pubmed-meshheading:21555814-HIV-1,
pubmed-meshheading:21555814-Humans,
pubmed-meshheading:21555814-Molecular Sequence Data,
pubmed-meshheading:21555814-Mutation,
pubmed-meshheading:21555814-Predictive Value of Tests,
pubmed-meshheading:21555814-Receptors, CCR5,
pubmed-meshheading:21555814-Receptors, CXCR4,
pubmed-meshheading:21555814-Reverse Transcriptase Inhibitors,
pubmed-meshheading:21555814-Treatment Outcome,
pubmed-meshheading:21555814-Triazoles,
pubmed-meshheading:21555814-Tropism
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pubmed:year |
2011
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pubmed:articleTitle |
Mutations in gp41 are correlated with coreceptor tropism but do not improve prediction methods substantially.
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pubmed:affiliation |
Max Planck Institute for Informatics, Saarbrücken, Germany. athielen@mpi-inf.mpg.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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