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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2011-6-3
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pubmed:abstractText |
Two clinical Staphylococcus aureus isolates were investigated due to their unusual antimicrobial susceptibility pattern, i.e. erythromycin-susceptible but clindamycin-resistant. These isolates harboured identical copies of a plasmid-borne vga(A)(LC) gene not previously described in S. aureus. The native plasmids carrying vga(A)(LC) were transferable to a susceptible laboratory strain of S. aureus in vitro, in which they conferred resistance patterns similar to the parent isolates.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1872-7913
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2011 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
81-3
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pubmed:meshHeading |
pubmed-meshheading:21549571-ATP-Binding Cassette Transporters,
pubmed-meshheading:21549571-Adolescent,
pubmed-meshheading:21549571-Anti-Bacterial Agents,
pubmed-meshheading:21549571-Bacterial Proteins,
pubmed-meshheading:21549571-Child, Preschool,
pubmed-meshheading:21549571-Clindamycin,
pubmed-meshheading:21549571-Drug Resistance, Bacterial,
pubmed-meshheading:21549571-Erythromycin,
pubmed-meshheading:21549571-Female,
pubmed-meshheading:21549571-Genetic Variation,
pubmed-meshheading:21549571-Humans,
pubmed-meshheading:21549571-Male,
pubmed-meshheading:21549571-Microbial Sensitivity Tests,
pubmed-meshheading:21549571-Plasmids,
pubmed-meshheading:21549571-Soft Tissue Infections,
pubmed-meshheading:21549571-Staphylococcal Infections,
pubmed-meshheading:21549571-Staphylococcal Skin Infections,
pubmed-meshheading:21549571-Staphylococcus aureus,
pubmed-meshheading:21549571-Streptogramin A
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pubmed:year |
2011
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pubmed:articleTitle |
Two paediatric cases of skin and soft-tissue infections due to clindamycin-resistant Staphylococcus aureus carrying a plasmid-encoded vga(A) allelic variant for a putative efflux pump.
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pubmed:affiliation |
Microbiology Laboratory, A9601, Seattle Children's Hospital, 4800 Sand Point Way, NE, Seattle, WA 98105, USA. xuan.qin@seattlechildrens.org
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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