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rdf:type |
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lifeskim:mentions |
umls-concept:C0005854,
umls-concept:C0032214,
umls-concept:C0035820,
umls-concept:C0038454,
umls-concept:C0205099,
umls-concept:C0205178,
umls-concept:C0277785,
umls-concept:C0600138,
umls-concept:C1517004,
umls-concept:C1552644,
umls-concept:C1823153,
umls-concept:C2349976
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|
pubmed:issue |
7
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|
pubmed:dateCreated |
2011-6-28
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|
pubmed:abstractText |
Phosphoinositide 3-kinase (PI3K)-? is linked to inflammation and oxidative stress. This study was conducted to investigate the role of the PI3K? in the blood-brain barrier dysfunction and brain damage induced by focal cerebral ischemia/reperfusion.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1524-4628
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2033-44
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pubmed:meshHeading |
pubmed-meshheading:21546487-Animals,
pubmed-meshheading:21546487-Blood-Brain Barrier,
pubmed-meshheading:21546487-Brain,
pubmed-meshheading:21546487-Class Ib Phosphatidylinositol 3-Kinase,
pubmed-meshheading:21546487-Infarction, Middle Cerebral Artery,
pubmed-meshheading:21546487-Inflammation,
pubmed-meshheading:21546487-Matrix Metalloproteinase 9,
pubmed-meshheading:21546487-Mice,
pubmed-meshheading:21546487-Mice, Inbred C57BL,
pubmed-meshheading:21546487-Mice, Knockout,
pubmed-meshheading:21546487-NF-kappa B,
pubmed-meshheading:21546487-Neutrophils,
pubmed-meshheading:21546487-Oxidative Stress,
pubmed-meshheading:21546487-Reperfusion Injury,
pubmed-meshheading:21546487-Stroke
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pubmed:year |
2011
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pubmed:articleTitle |
Phosphatidylinositol-3-kinase gamma plays a central role in blood-brain barrier dysfunction in acute experimental stroke.
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pubmed:affiliation |
Department of Neurosurgery, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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