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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2011-6-29
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pubmed:abstractText |
Sympathetic regulation of cardiac contractility is mediated in part by ?(1)-adrenergic receptors (ARs), and the ?(1A)-subtype has been implicated in the pathogenesis of cardiac hypertrophy. However, little is known about ?(1A)-AR signalling pathways in ventricular myocardium. The aim of this study was to determine the signalling pathway that mediates ?(1A)-AR-coupled cardiac contractility.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adra1a protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Adrenergic alpha-1 Receptor Agonists,
http://linkedlifedata.com/resource/pubmed/chemical/Phospholipase C beta,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Adrenergic, alpha-1,
http://linkedlifedata.com/resource/pubmed/chemical/Snapin protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/TRPC Cation Channels,
http://linkedlifedata.com/resource/pubmed/chemical/Trpc6 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Vesicular Transport Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/transient receptor potential...
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1755-3245
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pubmed:author |
pubmed-author:AllenDavid GDG,
pubmed-author:FatkinDianeD,
pubmed-author:FeneleyMichaelM,
pubmed-author:FriedrichOliverO,
pubmed-author:GrahamRobert MRM,
pubmed-author:IismaaSiiri ESE,
pubmed-author:MohlMarion CMC,
pubmed-author:Nikolova-KrstevskiVesnaV,
pubmed-author:WagnerSoerenS,
pubmed-author:WuJianxinJ,
pubmed-author:XiaoXiao-HuiXH,
pubmed-author:YuZe-YanZY
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
310-9
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pubmed:meshHeading |
pubmed-meshheading:21546445-Adrenergic alpha-1 Receptor Agonists,
pubmed-meshheading:21546445-Analysis of Variance,
pubmed-meshheading:21546445-Animals,
pubmed-meshheading:21546445-COS Cells,
pubmed-meshheading:21546445-Calcium Signaling,
pubmed-meshheading:21546445-Cell Membrane,
pubmed-meshheading:21546445-Cercopithecus aethiops,
pubmed-meshheading:21546445-Death, Sudden, Cardiac,
pubmed-meshheading:21546445-Disease Models, Animal,
pubmed-meshheading:21546445-Dose-Response Relationship, Drug,
pubmed-meshheading:21546445-HEK293 Cells,
pubmed-meshheading:21546445-Heart Diseases,
pubmed-meshheading:21546445-Humans,
pubmed-meshheading:21546445-Male,
pubmed-meshheading:21546445-Mice,
pubmed-meshheading:21546445-Mice, Transgenic,
pubmed-meshheading:21546445-Myocardial Contraction,
pubmed-meshheading:21546445-Myocytes, Cardiac,
pubmed-meshheading:21546445-Phospholipase C beta,
pubmed-meshheading:21546445-Protein Transport,
pubmed-meshheading:21546445-RNA Interference,
pubmed-meshheading:21546445-Rats,
pubmed-meshheading:21546445-Receptors, Adrenergic, alpha-1,
pubmed-meshheading:21546445-TRPC Cation Channels,
pubmed-meshheading:21546445-Time Factors,
pubmed-meshheading:21546445-Transfection,
pubmed-meshheading:21546445-Vesicular Transport Proteins
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pubmed:year |
2011
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pubmed:articleTitle |
Regulation of murine cardiac contractility by activation of ?(1A)-adrenergic receptor-operated Ca(2+) entry.
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pubmed:affiliation |
Molecular Cardiology and Biophysics Division, Victor Chang Cardiac Research Institute, Lowy Packer Building, 405 Liverpool St, Darlinghurst, NSW 2010, Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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