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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0022646,
umls-concept:C0185117,
umls-concept:C0205462,
umls-concept:C0220912,
umls-concept:C0220913,
umls-concept:C0242643,
umls-concept:C0450127,
umls-concept:C0522536,
umls-concept:C0599918,
umls-concept:C1413882,
umls-concept:C2757068,
umls-concept:C2911684
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|
pubmed:issue |
10
|
|
pubmed:dateCreated |
2011-5-5
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|
pubmed:abstractText |
Susceptibility to calcineurin inhibitor nephrotoxicity (CNIT) after solid organ transplantation could be related to an interindividual variability in renal expression and function of the metabolizing cytochrome P450 3A5 (CYP3A5) isoenzyme and of the multidrug efflux transporter P-glycoprotein (P-gp, ABCB1).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1534-6080
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pubmed:author |
|
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pubmed:issnType |
Electronic
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pubmed:day |
27
|
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1098-102
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pubmed:meshHeading |
pubmed-meshheading:21544031-Adult,
pubmed-meshheading:21544031-Aged,
pubmed-meshheading:21544031-Belgium,
pubmed-meshheading:21544031-Biopsy,
pubmed-meshheading:21544031-Calcineurin,
pubmed-meshheading:21544031-Case-Control Studies,
pubmed-meshheading:21544031-Chi-Square Distribution,
pubmed-meshheading:21544031-Cytochrome P-450 CYP3A,
pubmed-meshheading:21544031-Humans,
pubmed-meshheading:21544031-Hyalin,
pubmed-meshheading:21544031-Immunohistochemistry,
pubmed-meshheading:21544031-Immunosuppressive Agents,
pubmed-meshheading:21544031-Kidney,
pubmed-meshheading:21544031-Kidney Diseases,
pubmed-meshheading:21544031-Kidney Transplantation,
pubmed-meshheading:21544031-Middle Aged,
pubmed-meshheading:21544031-P-Glycoprotein,
pubmed-meshheading:21544031-Polymorphism, Single Nucleotide,
pubmed-meshheading:21544031-Retrospective Studies,
pubmed-meshheading:21544031-Tacrolimus,
pubmed-meshheading:21544031-Transplantation, Homologous
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pubmed:year |
2011
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pubmed:articleTitle |
Expression of CYP3A5 and P-glycoprotein in renal allografts with histological signs of calcineurin inhibitor nephrotoxicity.
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pubmed:affiliation |
Department of Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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