| pubmed-article:2154292 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2154292 | lifeskim:mentions | umls-concept:C0032659 | lld:lifeskim |
| pubmed-article:2154292 | lifeskim:mentions | umls-concept:C0025937 | lld:lifeskim |
| pubmed-article:2154292 | lifeskim:mentions | umls-concept:C0065911 | lld:lifeskim |
| pubmed-article:2154292 | lifeskim:mentions | umls-concept:C0037083 | lld:lifeskim |
| pubmed-article:2154292 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2154292 | pubmed:dateCreated | 1990-3-19 | lld:pubmed |
| pubmed-article:2154292 | pubmed:abstractText | The pineal hormone melatonin times seasonal alterations in reproductive function in photoperiodic mammals. In white-footed mice, there is variation in responsiveness to the reproductive effects of melatonin between populations originating in different locations; mice from Connecticut (CT) respond normally to melatonin, while mice from Georgia (GA) appear insensitive to melatonin. In the present paper, we compare melatonin receptor distribution and a second messenger response to melatonin in white-footed mice from CT and GA. Specific binding of 125I-labeled melatonin (I-MEL) was observed in a variety of brain regions in each population, but there were no consistent differences in the distribution or intensity of I-MEL binding between the populations. Furthermore, melatonin inhibited forskolin-stimulated cAMP accumulation in median eminence/pars tuberalis explants from both populations. These results suggest that insensitivity to melatonin in GA mice is not due to a gross defect in melatonin receptors or receptor-effector coupling. | lld:pubmed |
| pubmed-article:2154292 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2154292 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2154292 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2154292 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2154292 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2154292 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2154292 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2154292 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2154292 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2154292 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:2154292 | pubmed:issn | 0006-8993 | lld:pubmed |
| pubmed-article:2154292 | pubmed:author | pubmed-author:ReppertS MSM | lld:pubmed |
| pubmed-article:2154292 | pubmed:author | pubmed-author:CarltonM LML | lld:pubmed |
| pubmed-article:2154292 | pubmed:author | pubmed-author:WeaverD RDR | lld:pubmed |
| pubmed-article:2154292 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2154292 | pubmed:day | 8 | lld:pubmed |
| pubmed-article:2154292 | pubmed:volume | 506 | lld:pubmed |
| pubmed-article:2154292 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2154292 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2154292 | pubmed:pagination | 353-7 | lld:pubmed |
| pubmed-article:2154292 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:2154292 | pubmed:meshHeading | pubmed-meshheading:2154292-... | lld:pubmed |
| pubmed-article:2154292 | pubmed:meshHeading | pubmed-meshheading:2154292-... | lld:pubmed |
| pubmed-article:2154292 | pubmed:meshHeading | pubmed-meshheading:2154292-... | lld:pubmed |
| pubmed-article:2154292 | pubmed:meshHeading | pubmed-meshheading:2154292-... | lld:pubmed |
| pubmed-article:2154292 | pubmed:meshHeading | pubmed-meshheading:2154292-... | lld:pubmed |
| pubmed-article:2154292 | pubmed:meshHeading | pubmed-meshheading:2154292-... | lld:pubmed |
| pubmed-article:2154292 | pubmed:meshHeading | pubmed-meshheading:2154292-... | lld:pubmed |
| pubmed-article:2154292 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2154292 | pubmed:articleTitle | Melatonin receptors and signal transduction in melatonin-sensitive and melatonin-insensitive populations of white-footed mice (Peromyscus leucopus). | lld:pubmed |
| pubmed-article:2154292 | pubmed:affiliation | Laboratory of Developmental Chronobiology, Children's Service, Massachusetts General Hospital, Boston 02114. | lld:pubmed |
| pubmed-article:2154292 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2154292 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2154292 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2154292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2154292 | lld:pubmed |
