21542403

Source:http://linkedlifedata.com/resource/pubmed/id/21542403

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0238605, umls-concept:C0582175, umls-concept:C0694890
pubmed:issue	4
pubmed:dateCreated	2011-5-5
pubmed:abstractText	The RET proto-oncogene (REarranged during Transfection; RET) plays an important role in the causation of many thyroid tumours. Germline RET proto-oncogene missense mutations have been clearly linked to medullary thyroid carcinoma (MTC) and the inherited cancer syndrome multiple endocrine neoplasia type 2 (MEN2A, MEN2B).
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/2984854R
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Codon, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-ret
pubmed:status	MEDLINE
pubmed:month	Nov
pubmed:issn	0038-2361
pubmed:author	pubmed-author:MooreS WSW, pubmed-author:ZaahlM GMG
pubmed:issnType	Print
pubmed:volume	48
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	127-31
pubmed:meshHeading	pubmed-meshheading:21542403-Adolescent, pubmed-meshheading:21542403-Adult, pubmed-meshheading:21542403-Case-Control Studies, pubmed-meshheading:21542403-Child, pubmed-meshheading:21542403-Child, Preschool, pubmed-meshheading:21542403-Codon, pubmed-meshheading:21542403-Cohort Studies, pubmed-meshheading:21542403-Female, pubmed-meshheading:21542403-Genetic Variation, pubmed-meshheading:21542403-Humans, pubmed-meshheading:21542403-Infant, pubmed-meshheading:21542403-Infant, Newborn, pubmed-meshheading:21542403-Male, pubmed-meshheading:21542403-Middle Aged, pubmed-meshheading:21542403-Multiple Endocrine Neoplasia Type 2a, pubmed-meshheading:21542403-Point Mutation, pubmed-meshheading:21542403-Polymerase Chain Reaction, pubmed-meshheading:21542403-Proto-Oncogene Proteins c-ret, pubmed-meshheading:21542403-Risk Factors, pubmed-meshheading:21542403-South Africa
pubmed:year	2010
pubmed:articleTitle	Chasing the ubiquitous RET proto-oncogene in South African MEN2 families--implications for the surgeon.
pubmed:affiliation	Division of Paediatric Surgery, Department of Surgical Sciences, Stellenbosch University, Tygerberg, W Cape.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't