Source:http://linkedlifedata.com/resource/pubmed/id/21541879
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
12
|
| pubmed:dateCreated |
2011-5-4
|
| pubmed:abstractText |
The objective of this study was to (1) examine the relationship between nitrate (NO?-N) levels in public water supplies and risk of death from childhood brain tumors (CBT) and (2) determine whether calcium (Ca) and magnesium (Mg) levels in drinking water might modify the effects of NO?-N on development of CBT. A matched cancer case-control study was used to investigate the relationship between the risk of death attributed to CBT and exposure to NO?-N in drinking water in Taiwan. All CBT deaths of Taiwan residents from 1999 through 2008 were obtained from the Bureau of Vital Statistics of the Taiwan Provincial Department of Health. Controls were deaths from other causes and were pair-matched to the cases by gender, year of birth, and year of death. Information on the levels of nitrate-nitrogen NO?-N, Ca, and Mg in drinking water were collected from Taiwan Water Supply Corporation. The municipality of residence for CBT cases and controls was presumed to be the source of the subject's NO?-N, Ca, and Mg exposure via drinking water. Relative to individuals whose NO?-N exposure level was ? 0.31 ppm, and the adjusted odds ration (OR) (95% confidence interval [CI]) for CBT occurrence was 1.4 (1.07-1.84) for individuals who resided in municipalities served by drinking water with a NO?-N exposure > 0.31 ppm. No significant effect modification was observed by Ca and Mg intake via drinking water. Data suggest that exposure to NO?-N in drinking water is associated with a higher risk of CBT development in Taiwan.
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| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Jan
|
| pubmed:issn |
1528-7394
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
74
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
769-78
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| pubmed:meshHeading |
pubmed-meshheading:21541879-Adolescent,
pubmed-meshheading:21541879-Brain Neoplasms,
pubmed-meshheading:21541879-Calcium,
pubmed-meshheading:21541879-Case-Control Studies,
pubmed-meshheading:21541879-Child,
pubmed-meshheading:21541879-Child, Preschool,
pubmed-meshheading:21541879-Drinking,
pubmed-meshheading:21541879-Female,
pubmed-meshheading:21541879-Humans,
pubmed-meshheading:21541879-Infant,
pubmed-meshheading:21541879-Infant, Newborn,
pubmed-meshheading:21541879-Magnesium,
pubmed-meshheading:21541879-Male,
pubmed-meshheading:21541879-Nitrates,
pubmed-meshheading:21541879-Odds Ratio,
pubmed-meshheading:21541879-Risk Factors,
pubmed-meshheading:21541879-Taiwan,
pubmed-meshheading:21541879-Water Pollutants, Chemical,
pubmed-meshheading:21541879-Water Supply,
pubmed-meshheading:21541879-Young Adult
|
| pubmed:year |
2011
|
| pubmed:articleTitle |
Nitrates in drinking water and the risk of death from childhood brain tumors in Taiwan.
|
| pubmed:affiliation |
Department of Diagnostic Radiology, Chang Gung Memorial Hospital at Chiayi, Chang Gung University College of Medicine, Taiwan.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|