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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2011-5-4
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pubmed:abstractText |
High myopia is a severe hereditary ocular disease leading to blindness. LAMA1 (alpha subunit of laminin) is a promising candidate gene for high myopia present in the MYP2 (myopia 2) region. The purpose of this study was to determine if high myopia is associated with single nucleotide polymorphism (SNP) variants in LAMA1 in Chinese subjects.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1090-0535
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1003-10
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pubmed:meshHeading |
pubmed-meshheading:21541277-Adult,
pubmed-meshheading:21541277-Asian Continental Ancestry Group,
pubmed-meshheading:21541277-Case-Control Studies,
pubmed-meshheading:21541277-Cornea,
pubmed-meshheading:21541277-DNA,
pubmed-meshheading:21541277-DNA Primers,
pubmed-meshheading:21541277-Female,
pubmed-meshheading:21541277-Gene Expression,
pubmed-meshheading:21541277-Gene Frequency,
pubmed-meshheading:21541277-Genetic Diseases, Inborn,
pubmed-meshheading:21541277-Genetic Predisposition to Disease,
pubmed-meshheading:21541277-Genotype,
pubmed-meshheading:21541277-Humans,
pubmed-meshheading:21541277-Laminin,
pubmed-meshheading:21541277-Linkage Disequilibrium,
pubmed-meshheading:21541277-Male,
pubmed-meshheading:21541277-Middle Aged,
pubmed-meshheading:21541277-Myopia,
pubmed-meshheading:21541277-Polymerase Chain Reaction,
pubmed-meshheading:21541277-Polymorphism, Single Nucleotide,
pubmed-meshheading:21541277-Promoter Regions, Genetic
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pubmed:year |
2011
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pubmed:articleTitle |
The association of a single nucleotide polymorphism in the promoter region of the LAMA1 gene with susceptibility to Chinese high myopia.
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pubmed:affiliation |
Eye Center of Beijing Tongren Hospital of Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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