Source:http://linkedlifedata.com/resource/pubmed/id/21537169
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
2011-6-9
|
pubmed:abstractText |
Reactive oxygen species (ROS) have an important function in blood cell homeostasis and hematopoietic diseases. Recent discoveries concerning how ROS are generated and regulated in mitochondria via the mitochondrial permeability transition pore (mPTP) and the new phenomenon, superoxide flashes, and ROS-induced ROS release, have not been investigated in hematopoietic stem and progenitor cells, but likely have important implications for their regulation and survival. Here we relate our opinions about these potential implications.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Mitochondrial Membrane Transport...,
http://linkedlifedata.com/resource/pubmed/chemical/Reactive Oxygen Species,
http://linkedlifedata.com/resource/pubmed/chemical/Superoxides,
http://linkedlifedata.com/resource/pubmed/chemical/mitochondrial permeability...
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
1531-7048
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:volume |
18
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
208-13
|
pubmed:meshHeading |
pubmed-meshheading:21537169-Animals,
pubmed-meshheading:21537169-Apoptosis,
pubmed-meshheading:21537169-Hematopoietic Stem Cells,
pubmed-meshheading:21537169-Humans,
pubmed-meshheading:21537169-Mitochondrial Membrane Transport Proteins,
pubmed-meshheading:21537169-Reactive Oxygen Species,
pubmed-meshheading:21537169-Superoxides
|
pubmed:year |
2011
|
pubmed:articleTitle |
Superoxide flashes, reactive oxygen species, and the mitochondrial permeability transition pore: potential implications for hematopoietic stem cell function.
|
pubmed:affiliation |
Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana 46202-5181, USA. cmantel@iupui.edu
|
pubmed:publicationType |
Journal Article,
Review,
Research Support, N.I.H., Extramural
|