Linked Life Data

21532519

Source:http://linkedlifedata.com/resource/pubmed/id/21532519

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2011-6-28
pubmed:abstractText
Age-related macular degeneration (AMD) is the main cause of legal blindness in older patients in developed countries, and geographic atrophy (GA) represents the advanced form of dry AMD. Although it accounts for one third of the cases of late AMD and is responsible for 20% of the cases of severe visual loss due to the disorder. GA currently lacks effective treatment, whereas antiangiogenic therapies have been shown to be successful in managing choroidal neovascularization, the other form of late AMD. Recent advances in GA epidemiology, etiology, genetics, and imaging techniques have renewed the interest in this entity, which is a cause of progressive visual loss even in treated patients with neovascular AMD. This knowledge has triggered many clinical trials targeting different molecules shown to be associated with the disease, and it is hoped that this research will translate into effective drugs for GA in the near future.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1538-9235
pubmed:author
pubmed:copyrightInfo
Copyright © 2011 American Academy of Optometry
pubmed:issnType
Electronic
pubmed:volume
88
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
881-9
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Update on geographic atrophy in age-related macular degeneration.
pubmed:affiliation
Institut de la màcula i la retina, Centre Mèdic Teknon, Barcelona, Spain. biarnes@oo.upc.edu
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't