Source:http://linkedlifedata.com/resource/pubmed/id/21530827
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2011-5-2
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pubmed:abstractText |
For the past century, subcutaneous allergen-specific immunotherapy has been the state-of-the-art treatment for IgE-mediated allergic disease. Current research on allergen-specific immunotherapy is focused on enhancing its efficacy, safety, and patient convenience with the goal of offering a broadly accepted treatment option. There is a growing interest in intralymphatic allergen-specific immunotherapy because it is a highly efficacious and safe treatment route that requires only 3 injections. Concurrently, epicutaneous allergen-specific immunotherapy is attracting increasing attention because of its capacity to offer a safe, needle-free, and potentially self-administrable treatment option for IgE-mediated allergic diseases. In this article, we discuss the principles and immunologic rationale of these unconventional routes of allergen-specific immunotherapy while highlighting their developmental process and clinical relevance.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1557-8607
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2011 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
391-406, xi
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pubmed:meshHeading |
pubmed-meshheading:21530827-Allergens,
pubmed-meshheading:21530827-Animals,
pubmed-meshheading:21530827-Desensitization, Immunologic,
pubmed-meshheading:21530827-Drug Administration Routes,
pubmed-meshheading:21530827-Humans,
pubmed-meshheading:21530827-Injections, Intralymphatic,
pubmed-meshheading:21530827-Skin
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pubmed:year |
2011
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pubmed:articleTitle |
Novel administration routes for allergen-specific immunotherapy: a review of intralymphatic and epicutaneous allergen-specific immunotherapy.
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pubmed:affiliation |
Clinical Trials Center, Center for Clinical Research, University and University Hospital Zürich, Moussonstrasse 2, 8091 Zürich, Switzerland.
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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