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pubmed-article:2152994pubmed:abstractTextA major protein of Mr 68,000 with a previously described protein kinase activity (PK68), which is induced in HCMV-infected cells, is shown to be virus encoded by means of hybrid selection. The gene coding for the corresponding 4-kb mRNA was located within map units 0.510 and 0.525. This location is the same as that of pp65, a structural protein with no attributed function. The early nature of the protein was confirmed with its mRNA first appearing 3 hr after infection under cycloheximide reversal and phosphonoacetic acid blocking conditions. Another mRNA, 97 nucleotides smaller and 5' coterminal with PK68, which codes for a Mr 52,000 protein, was also observed.lld:pubmed
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pubmed-article:2152994pubmed:articleTitleGenomic location of a human cytomegalovirus protein with protein kinase activity (PK68).lld:pubmed
pubmed-article:2152994pubmed:affiliationUnité de Virologie Médicale, Institut Pasteur, Paris, France.lld:pubmed
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