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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2011-6-10
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pubmed:abstractText |
An imbalance in matrix metalloproteases (MMPs) and tissue inhibitors of MMPs (TIMPs) contributes to chronic obstructive pulmonary disease (COPD) development. Longitudinal studies investigating Single Nucleotide Polymorphisms (SNPs) in MMPs and TIMPs with respect to COPD development and lung function decline in the general population are lacking.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-10598806,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-10712992,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-10807873,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-11029344,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-11114309,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-11254539,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-11435239,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-11708786,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-11875051,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-12882441,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-14631556,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-14685227,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-15297300,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-15879414,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-15994390,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-16061701,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-16126934,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-16308335,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-16769715,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-16905636,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-16921115,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-20018959,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-3499295,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-8620705,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-9659349,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-9759652,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21524282-9850057
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/MMP1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/MMP12 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/MMP2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 1,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 12,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 2,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 9,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinases, Secreted,
http://linkedlifedata.com/resource/pubmed/chemical/Tissue Inhibitor of...
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pubmed:status |
MEDLINE
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pubmed:issn |
1465-993X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
57
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pubmed:meshHeading |
pubmed-meshheading:21524282-Adult,
pubmed-meshheading:21524282-Aged,
pubmed-meshheading:21524282-Analysis of Variance,
pubmed-meshheading:21524282-European Continental Ancestry Group,
pubmed-meshheading:21524282-Female,
pubmed-meshheading:21524282-Forced Expiratory Volume,
pubmed-meshheading:21524282-Gene Frequency,
pubmed-meshheading:21524282-Genetic Predisposition to Disease,
pubmed-meshheading:21524282-Humans,
pubmed-meshheading:21524282-Linear Models,
pubmed-meshheading:21524282-Lung,
pubmed-meshheading:21524282-Male,
pubmed-meshheading:21524282-Matrix Metalloproteinase 1,
pubmed-meshheading:21524282-Matrix Metalloproteinase 12,
pubmed-meshheading:21524282-Matrix Metalloproteinase 2,
pubmed-meshheading:21524282-Matrix Metalloproteinase 9,
pubmed-meshheading:21524282-Matrix Metalloproteinases, Secreted,
pubmed-meshheading:21524282-Middle Aged,
pubmed-meshheading:21524282-Netherlands,
pubmed-meshheading:21524282-Phenotype,
pubmed-meshheading:21524282-Polymorphism, Single Nucleotide,
pubmed-meshheading:21524282-Prospective Studies,
pubmed-meshheading:21524282-Pulmonary Disease, Chronic Obstructive,
pubmed-meshheading:21524282-Risk Assessment,
pubmed-meshheading:21524282-Risk Factors,
pubmed-meshheading:21524282-Tissue Inhibitor of Metalloproteinase-1
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pubmed:year |
2011
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pubmed:articleTitle |
Genetic variation in TIMP1 but not MMPs predict excess FEV1 decline in two general population-based cohorts.
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pubmed:affiliation |
Department of Epidemiology, University of Groningen, Groningen, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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