Linked Life Data

21517120

Source:http://linkedlifedata.com/resource/pubmed/id/21517120

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2011-5-18
pubmed:abstractText
Efficient syntheses of several members of a new class of symmetric, monocarboxylate-functionalized cyanine dyes have been developed. The synthesis is a simple two-step method, typically with greater than 60% yield and easy final product purification. The new monocarboxylate-functionalized cyanine dyes exhibit excellent water solubility and similar excitation and emission properties to those of Cy5 and Alexa Fluor 647. The application of the new dyes in cellular imaging has been demonstrated through direct conjugating of the dye with an antibody, then imaging of microtubules inside cells, visualized by near-infrared fluorescence microscopy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1520-4812
pubmed:author
pubmed:issnType
Electronic
pubmed:day
18
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
865-9
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Facile synthesis of symmetric, monofunctional cyanine dyes for imaging applications.
pubmed:affiliation
Life Technologies, 29851 Willow Creek Road, Eugene, OR 97402, United States. lai-qiang.ying@lifetech.com
pubmed:publicationType
Journal Article