Linked Life Data

21510935

Source:http://linkedlifedata.com/resource/pubmed/id/21510935

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2011-6-9
pubmed:abstractText
DEPP was initially cloned from the human endometrial stromal cell cDNA library, but the transcriptional regulation of DEPP remains largely unknown. We demonstrate here that expression of DEPP is FoxO-dependent in human endothelial cells. Two functional FoxO-responsive elements are identified in the DEPP promoter. Hypoxia stimulates DEPP expression in the endothelial cell line EA.hy926. Hypoxia-induced upregulation of DEPP is dependent on FoxO expression. We conclude that DEPP is regulated at the level of transcription by FoxO in human vascular endothelial cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1873-3468
pubmed:author
pubmed:copyrightInfo
Copyright © 2011 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
23
pubmed:volume
585
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1796-800
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
FoxO regulates expression of decidual protein induced by progesterone (DEPP) in human endothelial cells.
pubmed:affiliation
Key Laboratory of Cardiovascular Disease and Molecular Intervention, Department of Pathophysiology, Nanjing Medical University, Nanjing, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't