Linked Life Data

2150857

Source:http://linkedlifedata.com/resource/pubmed/id/2150857

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
1991-5-21
pubmed:abstractText
The severity of necrotic muscle and nerve lesions in the ischemic hind limbs of diabetic and nondiabetic rats was compared. Chronic limb ischemia was induced by repetitive, daily for up to 8 weeks, intraperitoneal injections of serotonin in rats with ligated right femoral artery. Light microscopic examination and lesion severity grading was performed on sections taken from several right hind limb muscles and the right tibial nerve. Overall, muscle was less damaged in diabetic than in nondiabetic rats. However, muscle was damaged more than nerve in all but diabetic rats with severe chronic ischemia. Muscle vulnerability to ischemic damage is decreased in diabetes, presumably due to abundance of glucose and other energy substrates which can be utilized during ischemia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0022-510X
pubmed:author
pubmed:issnType
Print
pubmed:volume
99
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
147-52
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Muscle vulnerability to ischemic damage is decreased in experimental diabetes mellitus.
pubmed:affiliation
James A. Haley Veterans Hospital, University of South Florida College of Medicine, Tampa 33612.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, Non-P.H.S.