| pubmed-article:21504904 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21504904 | lifeskim:mentions | umls-concept:C0162741 | lld:lifeskim |
| pubmed-article:21504904 | lifeskim:mentions | umls-concept:C0026237 | lld:lifeskim |
| pubmed-article:21504904 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:21504904 | lifeskim:mentions | umls-concept:C0205341 | lld:lifeskim |
| pubmed-article:21504904 | lifeskim:mentions | umls-concept:C0162782 | lld:lifeskim |
| pubmed-article:21504904 | lifeskim:mentions | umls-concept:C0205224 | lld:lifeskim |
| pubmed-article:21504904 | lifeskim:mentions | umls-concept:C1519595 | lld:lifeskim |
| pubmed-article:21504904 | pubmed:issue | 24 | lld:pubmed |
| pubmed-article:21504904 | pubmed:dateCreated | 2011-6-13 | lld:pubmed |
| pubmed-article:21504904 | pubmed:abstractText | In plant organelles, RNA editing is a post-transcriptional mechanism that converts specific cytidines to uridines in RNA of both mitochondria and plastids, altering the information encoded by the gene. The cytidine to be edited is determined by a cis-element surrounding the editing site that is specifically recognized and bound by a trans-acting factor. All the trans-acting editing factors identified so far in plant organelles are members of a large protein family, the pentatricopeptide repeat (PPR) proteins. We have identified the Organelle Transcript Processing 87 (OTP87) gene, which is required for RNA editing of the nad7-C24 and atp1-C1178 sites in Arabidopsis mitochondria. OTP87 encodes an E-subclass PPR protein with an unusually short E-domain. The recombinant protein expressed in Escherichia coli specifically binds to RNAs comprising 30 nucleotides upstream and 10 nucleotides downstream of the nad7-C24 and atp1-C1178 editing sites. The loss-of-function of OTP87 results in small plants with growth and developmental delays. In the otp87 mutant, the amount of assembled respiratory complex V (ATP synthase) is highly reduced compared with the wild type suggesting that the amino acid alteration in ATP1 caused by loss of editing at the atp1-C1178 site affects complex V assembly in mitochondria. | lld:pubmed |
| pubmed-article:21504904 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21504904 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21504904 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21504904 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:21504904 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21504904 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21504904 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21504904 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21504904 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21504904 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21504904 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:21504904 | pubmed:issn | 1083-351X | lld:pubmed |
| pubmed-article:21504904 | pubmed:author | pubmed-author:OkudaKenjiK | lld:pubmed |
| pubmed-article:21504904 | pubmed:author | pubmed-author:SmallIanI | lld:pubmed |
| pubmed-article:21504904 | pubmed:author | pubmed-author:ShikanaiToshi... | lld:pubmed |
| pubmed-article:21504904 | pubmed:author | pubmed-author:BrennickeAxel... | lld:pubmed |
| pubmed-article:21504904 | pubmed:author | pubmed-author:TakenakaMizuk... | lld:pubmed |
| pubmed-article:21504904 | pubmed:author | pubmed-author:TanzSandra... | lld:pubmed |
| pubmed-article:21504904 | pubmed:author | pubmed-author:HammaniKamelK | lld:pubmed |
| pubmed-article:21504904 | pubmed:author | pubmed-author:des... | lld:pubmed |
| pubmed-article:21504904 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21504904 | pubmed:day | 17 | lld:pubmed |
| pubmed-article:21504904 | pubmed:volume | 286 | lld:pubmed |
| pubmed-article:21504904 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21504904 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21504904 | pubmed:pagination | 21361-71 | lld:pubmed |
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| pubmed-article:21504904 | pubmed:meshHeading | pubmed-meshheading:21504904... | lld:pubmed |
| pubmed-article:21504904 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21504904 | pubmed:articleTitle | The pentatricopeptide repeat protein OTP87 is essential for RNA editing of nad7 and atp1 transcripts in Arabidopsis mitochondria. | lld:pubmed |
| pubmed-article:21504904 | pubmed:affiliation | Australian Research Council Centre of Excellence in Plant Energy Biology, University of Western Australia, Crawley 6009 Western Australia, Australia. khammani@uoregon.edu | lld:pubmed |
| pubmed-article:21504904 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21504904 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:21504904 | lld:entrezgene |
