Linked Life Data

21502390

Source:http://linkedlifedata.com/resource/pubmed/id/21502390

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2011-4-19
pubmed:abstractText
Ovarian cancer is the most lethal of the gynecologic malignancies. Because ovarian cancer symptoms are subtle and nonspecific, the diagnosis is often delayed until the disease is well advanced. Overall 5-year survival is a rather dismal 50% but can be improved to greater than 90% if the disease is confined to the ovary at the time of diagnosis (generally in fewer than 25% of patients). Effective screening tools are currently not available. Owing to the rather low incidence of the disease in the general population, potential screening tests must provide very high specificity to avoid unnecessary interventions in false-positive cases. This article reviews currently available serum biomarkers and imaging tests for the early detection of ovarian cancer and provides an outlook on the potential improvements in these noninvasive diagnostic tools that may lead to successful implementation in a screening program. Supplemental material: http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.11090563/-/DC1.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1527-1315
pubmed:author
pubmed:copyrightInfo
RSNA, 2011
pubmed:issnType
Electronic
pubmed:volume
259
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
329-45
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Early diagnosis of ovarian carcinoma: is a solution in sight?
pubmed:affiliation
Department of Radiology, Bio-X Program, Stanford University School of Medicine, 318 Campus Dr, Room E150, Stanford, CA 94305, USA.
pubmed:publicationType
Journal Article, Review