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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2011-5-5
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pubmed:abstractText |
Proteasome inhibitors have been found to suppress glioma cell proliferation and induce apoptosis, but the mechanisms are not fully elucidated. In this study we investigated the mechanisms underlying the apoptosis induced by the proteasome inhibitor MG-132 in glioma cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1745-7254
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pubmed:author |
|
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pubmed:issnType |
Electronic
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
619-25
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pubmed:meshHeading |
pubmed-meshheading:21499287-Animals,
pubmed-meshheading:21499287-Antineoplastic Agents,
pubmed-meshheading:21499287-Apoptosis,
pubmed-meshheading:21499287-Blotting, Western,
pubmed-meshheading:21499287-Cell Line, Tumor,
pubmed-meshheading:21499287-Cell Proliferation,
pubmed-meshheading:21499287-Cysteine Proteinase Inhibitors,
pubmed-meshheading:21499287-Dose-Response Relationship, Drug,
pubmed-meshheading:21499287-Glioma,
pubmed-meshheading:21499287-Inhibitory Concentration 50,
pubmed-meshheading:21499287-Leupeptins,
pubmed-meshheading:21499287-Oxidative Stress,
pubmed-meshheading:21499287-Proteasome Endopeptidase Complex,
pubmed-meshheading:21499287-Rats,
pubmed-meshheading:21499287-Reactive Oxygen Species,
pubmed-meshheading:21499287-Time Factors
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pubmed:year |
2011
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pubmed:articleTitle |
Proteasome inhibitor MG-132 induces C6 glioma cell apoptosis via oxidative stress.
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pubmed:affiliation |
Department of Neurosurgery, 1st Bethune Hospital of Jilin University, Changchun 130021, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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