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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2011-4-18
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pubmed:abstractText |
In breast cancer (BC), metastases to the central nervous system usually arise in women with advanced disease. Diagnosis of leptomeningeal (LM) metastasis is based on neurological symptoms, imaging studies and cytological detection of malignant cells in the cerebrospinal fluid (CSF). However, often these approaches are not sensitive enough to recognize leptomeninges involvement and subsequently to make a diagnosis of LM carcinomatosis. This study investigated the employment of reverse transcriptase-polymerase chain reaction (RT-PCR) for the human mammaglobin (hMAM) gene in a case of BC with cerebral metastases in which the involvement of the leptomeninges was in doubt.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1791-7530
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pubmed:author |
pubmed-author:AmorosoDomenicoD,
pubmed-author:BacigalupoBartolomeoB,
pubmed-author:CameriniAndreaA,
pubmed-author:CapelliniCesareC,
pubmed-author:CibeiEugenioE,
pubmed-author:DessantiPaoloP,
pubmed-author:DonoMariellaM,
pubmed-author:FedeliFrancoF,
pubmed-author:FerroPaolaP,
pubmed-author:FranceschiniMaria CristianaMC,
pubmed-author:RoncellaSilvioS
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pubmed:issnType |
Electronic
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1061-4
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:21498739-Breast Neoplasms,
pubmed-meshheading:21498739-Diagnosis, Differential,
pubmed-meshheading:21498739-Dura Mater,
pubmed-meshheading:21498739-Female,
pubmed-meshheading:21498739-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:21498739-Humans,
pubmed-meshheading:21498739-Magnetic Resonance Imaging,
pubmed-meshheading:21498739-Mammaglobin A,
pubmed-meshheading:21498739-Meningeal Neoplasms,
pubmed-meshheading:21498739-Middle Aged,
pubmed-meshheading:21498739-Neoplasm Proteins,
pubmed-meshheading:21498739-RNA, Messenger,
pubmed-meshheading:21498739-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:21498739-Uteroglobin
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pubmed:year |
2011
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pubmed:articleTitle |
Human mammaglobin transcript amplification for differential diagnosis in a breast cancer metastatic to dura mater.
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pubmed:affiliation |
Anatomia e Citoistologia Patologica, National Cancer Institute (IST), L.go R. Benzi, 10, 16132 Genova, Italy. mariella.dono@istge.it
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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