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rdf:type |
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lifeskim:mentions |
umls-concept:C0008976,
umls-concept:C0013080,
umls-concept:C0015780,
umls-concept:C0030705,
umls-concept:C0034656,
umls-concept:C0085732,
umls-concept:C0205082,
umls-concept:C0332161,
umls-concept:C0332173,
umls-concept:C0338656,
umls-concept:C0376558,
umls-concept:C0527316
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pubmed:issue |
1
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pubmed:dateCreated |
2011-4-18
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pubmed:abstractText |
Down syndrome (DS) patients share certain neuropathological features with Alzheimer disease patients. A randomized, double-blind, placebo-controlled study was performed to investigate the efficacy and safety of donepezil, an Alzheimer disease drug, for DS patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0091-2174
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pubmed:author |
pubmed-author:FukudaMasafumiM,
pubmed-author:HondaRyokoR,
pubmed-author:IkedaMasayukiM,
pubmed-author:ItohHiroshiH,
pubmed-author:KakeeNaokoN,
pubmed-author:KannoAtsushiA,
pubmed-author:KojimaMichioM,
pubmed-author:KondohTatsuroT,
pubmed-author:KosakiRikaR,
pubmed-author:MoriuchiHiroyukiH,
pubmed-author:NagaiToshiroT,
pubmed-author:NakaneHideyukiH,
pubmed-author:NakashimaMikiroM,
pubmed-author:NoguchiMitsuruM,
pubmed-author:NozakiHidetsuguH,
pubmed-author:OkuyamaTorayukiT,
pubmed-author:SasakiHitoshiH,
pubmed-author:ShibataYoshisadaY
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pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
71-89
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pubmed:meshHeading |
pubmed-meshheading:21495523-Activities of Daily Living,
pubmed-meshheading:21495523-Adult,
pubmed-meshheading:21495523-Cognition Disorders,
pubmed-meshheading:21495523-Double-Blind Method,
pubmed-meshheading:21495523-Down Syndrome,
pubmed-meshheading:21495523-Female,
pubmed-meshheading:21495523-Humans,
pubmed-meshheading:21495523-Indans,
pubmed-meshheading:21495523-Middle Aged,
pubmed-meshheading:21495523-Neuropsychological Tests,
pubmed-meshheading:21495523-Nootropic Agents,
pubmed-meshheading:21495523-Piperidines,
pubmed-meshheading:21495523-Quality of Life,
pubmed-meshheading:21495523-Treatment Outcome
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pubmed:year |
2011
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pubmed:articleTitle |
Donepezil significantly improves abilities in daily lives of female Down syndrome patients with severe cognitive impairment: a 24-week randomized, double-blind, placebo-controlled trial.
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pubmed:affiliation |
Department of Pediatrics, Nagasaki University Hospital, Japan. kontatsu@nagasaki-u.ac.jp
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial
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