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pubmed-article:21493743pubmed:abstractTextChildren with IgA nephropathy showing diffuse (>80%) mesangial proliferation are at high risk for end-stage renal failure (ESRF). A previous controlled trial showed that combination therapy consisting of prednisolone, azathioprine, heparin-warfarin, and dipyridamole early in the course of disease reduces immunologic renal injury and prevents the progression of sclerosed glomeruli. The objective of this study was to evaluate the long-term effectiveness of combination therapy in children with IgA nephropathy showing diffuse mesangial proliferation.lld:pubmed
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pubmed-article:21493743pubmed:articleTitleLong-term results of a randomized controlled trial in childhood IgA nephropathy.lld:pubmed
pubmed-article:21493743pubmed:affiliationDepartment of Nephrology, National Center for Child Health and Development, Setagaya, Tokyo, Japan.lld:pubmed
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pubmed-article:21493743pubmed:publicationTypeRandomized Controlled Triallld:pubmed
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