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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2011-6-9
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pubmed:abstractText |
Children with IgA nephropathy showing diffuse (>80%) mesangial proliferation are at high risk for end-stage renal failure (ESRF). A previous controlled trial showed that combination therapy consisting of prednisolone, azathioprine, heparin-warfarin, and dipyridamole early in the course of disease reduces immunologic renal injury and prevents the progression of sclerosed glomeruli. The objective of this study was to evaluate the long-term effectiveness of combination therapy in children with IgA nephropathy showing diffuse mesangial proliferation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1555-905X
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pubmed:author |
pubmed-author:HatayaHiroshiH,
pubmed-author:HondaMasatakaM,
pubmed-author:IijimaKazumotoK,
pubmed-author:IshikuraKenjiK,
pubmed-author:ItoShuichiS,
pubmed-author:Japanese Pediatric IgA Nephropathy Treatment Study Group,
pubmed-author:KameiKoichiK,
pubmed-author:NakanishiKoichiK,
pubmed-author:SaitoMariM,
pubmed-author:SakoMayumiM,
pubmed-author:YoshikawaNorishigeN
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pubmed:issnType |
Electronic
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1301-7
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pubmed:meshHeading |
pubmed-meshheading:21493743-Adolescent,
pubmed-meshheading:21493743-Anticoagulants,
pubmed-meshheading:21493743-Azathioprine,
pubmed-meshheading:21493743-Cell Proliferation,
pubmed-meshheading:21493743-Child,
pubmed-meshheading:21493743-Dipyridamole,
pubmed-meshheading:21493743-Disease Progression,
pubmed-meshheading:21493743-Drug Therapy, Combination,
pubmed-meshheading:21493743-Female,
pubmed-meshheading:21493743-Glomerulonephritis, IGA,
pubmed-meshheading:21493743-Heparin,
pubmed-meshheading:21493743-Humans,
pubmed-meshheading:21493743-Immunosuppressive Agents,
pubmed-meshheading:21493743-Japan,
pubmed-meshheading:21493743-Kaplan-Meier Estimate,
pubmed-meshheading:21493743-Kidney Failure, Chronic,
pubmed-meshheading:21493743-Kidney Glomerulus,
pubmed-meshheading:21493743-Male,
pubmed-meshheading:21493743-Prednisolone,
pubmed-meshheading:21493743-Proportional Hazards Models,
pubmed-meshheading:21493743-Prospective Studies,
pubmed-meshheading:21493743-Proteinuria,
pubmed-meshheading:21493743-Risk Assessment,
pubmed-meshheading:21493743-Risk Factors,
pubmed-meshheading:21493743-Severity of Illness Index,
pubmed-meshheading:21493743-Time Factors,
pubmed-meshheading:21493743-Treatment Outcome,
pubmed-meshheading:21493743-Warfarin
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pubmed:year |
2011
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pubmed:articleTitle |
Long-term results of a randomized controlled trial in childhood IgA nephropathy.
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pubmed:affiliation |
Department of Nephrology, National Center for Child Health and Development, Setagaya, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Meta-Analysis
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