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pubmed-article:21490708pubmed:abstractTextThe Asia-specific PLA2G7 994G-T transversion leads to V279F substitution within the lipoprotein-associated phospholipase-A2 (Lp-PLA?) and to absence of enzyme activity in plasma. This variant offers a unique natural experiment to assess the role of Lp-PLA? in the pathogenesis of coronary artery disease (CAD) in humans. Given conflicting results from mostly small studies, a large two-stage case-control study was warranted.lld:pubmed
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pubmed-article:21490708pubmed:articleTitleCarriage of the V279F null allele within the gene encoding Lp-PLA? is protective from coronary artery disease in South Korean males.lld:pubmed
pubmed-article:21490708pubmed:affiliationDivision of Cardiology, Cardiovascular Genome Center, Yonsei University College of Medicine, Yonsei, South Korea.lld:pubmed
pubmed-article:21490708pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:21490708pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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