21487429

Source:http://linkedlifedata.com/resource/pubmed/id/21487429

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0029925, umls-concept:C0041904, umls-concept:C0162638, umls-concept:C0667830, umls-concept:C1518174
pubmed:issue	8
pubmed:dateCreated	2011-4-13
pubmed:abstractText	Drug resistance is a major problem in ovarian cancer. Triggering apoptosis using death ligands such as tumour necrosis factor-related apoptosis inducing ligand (TRAIL) might overcome chemoresistance.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0370635
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Caspase 8, http://linkedlifedata.com/resource/pubmed/chemical/Cisplatin, http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins, http://linkedlifedata.com/resource/pubmed/chemical/TNF-Related Apoptosis-Inducing..., http://linkedlifedata.com/resource/pubmed/chemical/TNFSF10 protein, human
pubmed:status	MEDLINE
pubmed:month	Apr
pubmed:issn	1532-1827
pubmed:author	pubmed-author:DuikerE WEW, pubmed-author:ImaiH THT, pubmed-author:MeersmaG JGJ, pubmed-author:MeijerAA, pubmed-author:de JongSS, pubmed-author:de VriesE GEG, pubmed-author:van der BiltA R MAR, pubmed-author:van der ZeeA G JAG
pubmed:issnType	Electronic
pubmed:day	12
pubmed:volume	104
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1278-87
pubmed:meshHeading	pubmed-meshheading:21487429-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:21487429-Apoptosis, pubmed-meshheading:21487429-Carcinoma, pubmed-meshheading:21487429-Caspase 8, pubmed-meshheading:21487429-Cell Line, Tumor, pubmed-meshheading:21487429-Cisplatin, pubmed-meshheading:21487429-Drug Evaluation, Preclinical, pubmed-meshheading:21487429-Drug Resistance, Neoplasm, pubmed-meshheading:21487429-Female, pubmed-meshheading:21487429-Gene Expression Regulation, Enzymologic, pubmed-meshheading:21487429-Gene Expression Regulation, Neoplastic, pubmed-meshheading:21487429-Humans, pubmed-meshheading:21487429-Ovarian Neoplasms, pubmed-meshheading:21487429-Recombinant Proteins, pubmed-meshheading:21487429-TNF-Related Apoptosis-Inducing Ligand, pubmed-meshheading:21487429-Up-Regulation
pubmed:year	2011
pubmed:articleTitle	Drug-induced caspase 8 upregulation sensitises cisplatin-resistant ovarian carcinoma cells to rhTRAIL-induced apoptosis.
pubmed:affiliation	Department of Medical Oncology, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, Groningen 9713 GZ, The Netherlands.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't