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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2011-4-12
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pubmed:abstractText |
MicroRNAs (miRNAs) are noncoding RNAs inhibiting expression of numerous target genes by posttranscriptional regulation. miRNA-221 and miRNA-222 (miRNA-221/-222) expression is elevated in radioresistant tumor cell lines; however, it is not known whether and how miRNAs control cellular responses to ionizing irradiation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/MIRN221 microRNA, human,
http://linkedlifedata.com/resource/pubmed/chemical/MIRN222 microRNA, human,
http://linkedlifedata.com/resource/pubmed/chemical/MicroRNAs,
http://linkedlifedata.com/resource/pubmed/chemical/Oligonucleotides, Antisense,
http://linkedlifedata.com/resource/pubmed/chemical/PTEN Phosphohydrolase,
http://linkedlifedata.com/resource/pubmed/chemical/PTEN protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-akt
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1879-355X
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pubmed:author |
pubmed-author:CaoYongzhenY,
pubmed-author:IshiyamaHiromichiH,
pubmed-author:JiaZhifanZ,
pubmed-author:KangChunshengC,
pubmed-author:LimJ KJK,
pubmed-author:LinN SNS,
pubmed-author:LvZhonghongZ,
pubmed-author:PuPeiyuP,
pubmed-author:TehBin SBS,
pubmed-author:WangGuangxiuG,
pubmed-author:WangPingP,
pubmed-author:YangChunyingC,
pubmed-author:YuShizhuS,
pubmed-author:ZhangAnlingA,
pubmed-author:ZhangChunzhiC
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pubmed:copyrightInfo |
Copyright © 2011 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
80
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
240-8
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pubmed:meshHeading |
pubmed-meshheading:21481725-Apoptosis,
pubmed-meshheading:21481725-Base Sequence,
pubmed-meshheading:21481725-Cell Line, Tumor,
pubmed-meshheading:21481725-Gene Knockdown Techniques,
pubmed-meshheading:21481725-Humans,
pubmed-meshheading:21481725-MicroRNAs,
pubmed-meshheading:21481725-Oligonucleotides, Antisense,
pubmed-meshheading:21481725-PTEN Phosphohydrolase,
pubmed-meshheading:21481725-Proto-Oncogene Proteins c-akt,
pubmed-meshheading:21481725-Radiation Tolerance,
pubmed-meshheading:21481725-Tumor Stem Cell Assay
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pubmed:year |
2011
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pubmed:articleTitle |
MicroRNA-221 and -222 regulate radiation sensitivity by targeting the PTEN pathway.
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pubmed:affiliation |
Department of Neurosurgery, Tianjin Medical University General Hospital, Laboratory of Neuro-oncology, Tianjin Neurological Institute, Tianjin 300052, China.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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