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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
1991-1-31
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pubmed:abstractText |
We studied the left ventricular filling before and 15 minutes after sublingual absorption of one Nifedipine capsule in 33 untreated hypertensive patients (mean age: 68.6) without other cardiac disease and presenting an hypertensive access. This study was carried out with Doppler-echocardiography. Sample volume was set at the tips of mitral leaflets. The protocol included: early peak filling velocity (VE), atrial peak velocity (VA), mitral pressure half-time (T1/2), isovolumic relaxation time (TRIV), velocity time integral of total mitral curve (VTIT) and velocity time integral of atrial curve (VTIA). We also studied VE/VTIT ratio which has been correlated to peak filling rate/mitral stroke volume ratio in radionuclide angiography. RESULTS: [table: see text] The variations of VA/VE, VTIA/VTIT, VE/VTIT and T1/2 are statistically significant but decrease of TRIV is not significant. The arterial blood pressure decreases from 184/103 to 153/83 and cardiac rate increases from 81.8 to 87.9 beats/minute. CONCLUSION: On hypertensive emergencies sublingual nifedipine significantly improves rapid left ventricular filling without change of TRIV. Acceleration of cardiac rate is moderate.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0003-9683
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
83
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1119-22
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pubmed:dateRevised |
2009-2-13
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pubmed:meshHeading |
pubmed-meshheading:2148069-Administration, Sublingual,
pubmed-meshheading:2148069-Adult,
pubmed-meshheading:2148069-Aged,
pubmed-meshheading:2148069-Aged, 80 and over,
pubmed-meshheading:2148069-Blood Pressure,
pubmed-meshheading:2148069-Cardiomegaly,
pubmed-meshheading:2148069-Echocardiography, Doppler,
pubmed-meshheading:2148069-Female,
pubmed-meshheading:2148069-Humans,
pubmed-meshheading:2148069-Hypertension,
pubmed-meshheading:2148069-Male,
pubmed-meshheading:2148069-Middle Aged,
pubmed-meshheading:2148069-Nifedipine,
pubmed-meshheading:2148069-Stroke Volume
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pubmed:year |
1990
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pubmed:articleTitle |
[Action of sublingual nifedipine on left ventricular filling in hypertensive crisis].
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pubmed:affiliation |
Service de cardiologie, centre hospitalier général, Saint-Dié, France.
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pubmed:publicationType |
Journal Article,
English Abstract
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