Source:http://linkedlifedata.com/resource/pubmed/id/21476748
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
13
|
pubmed:dateCreated |
2011-4-11
|
pubmed:abstractText |
This paper examines the benefits of Michaelis-Menten model reduction techniques in stochastic tau-leaping simulations. Results show that although the conditions for the validity of the reductions for tau-leaping remain the same as those for the stochastic simulation algorithm (SSA), the reductions result in a substantial speed-up for tau-leaping under a different range of conditions than they do for SSA. The reason of this discrepancy is that the time steps for SSA and for tau-leaping are determined by different properties of system dynamics.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1089-7690
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:day |
7
|
pubmed:volume |
134
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
134112
|
pubmed:meshHeading |
pubmed-meshheading:21476748-Algorithms,
pubmed-meshheading:21476748-Animals,
pubmed-meshheading:21476748-Computer Simulation,
pubmed-meshheading:21476748-Drosophila,
pubmed-meshheading:21476748-Drosophila Proteins,
pubmed-meshheading:21476748-Enzymes,
pubmed-meshheading:21476748-Kinetics,
pubmed-meshheading:21476748-Models, Biological,
pubmed-meshheading:21476748-Period Circadian Proteins,
pubmed-meshheading:21476748-Stochastic Processes
|
pubmed:year |
2011
|
pubmed:articleTitle |
Michaelis-Menten speeds up tau-leaping under a wide range of conditions.
|
pubmed:affiliation |
Department of Computer Science, University of California, Santa Barbara, Santa Barbara, California 93106, USA. sheng@cs.ucsb.edu
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
|