Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2011-4-26
pubmed:abstractText
The colloidal stability of polymer-stabilized nanoparticles is critical for therapeutic use. However, phosphates in physiological media can induce polymer desorption and consequently flocculation. Colloidal characteristics of PEO-magnetite nanoparticles with different anchors for attaching PEO to magnetite were examined in PBS. The effects of the number of anchors, PEO molecular weight, and chain density were examined. It was observed that ammonium phosphonates anchored PEO to magnetite effectively in phosphate-containing solutions because of interactions between the phosphonates and magnetite. Additionally, a method to estimate the magnetite surface coverage was developed and was found to be critical to the prediction of colloidal stability. This is key to understanding how functionalized surfaces interact with their environment.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1520-5827
pubmed:author
pubmed:issnType
Electronic
pubmed:day
3
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5456-63
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Design of stable polyether-magnetite complexes in aqueous media: effects of the anchor group, molecular weight, and chain density.
pubmed:affiliation
Department of Chemical Engineering, Virginia Tech, Blacksburg, Virginia 24061, United States.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't