Linked Life Data

21474996

Source:http://linkedlifedata.com/resource/pubmed/id/21474996

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2011-6-15
pubmed:abstractText
Thirty years ago arachidonic (AA; 20:4 ? ( 5,8,11,14) ) and eicosapentaenoic (EPA; 20:5 ? ( 5,8,11,14,17) ) acids were identified as elicitors from the late blight pathogen, Phytophthora infestans, capable of triggering the dramatic shifts in isoprenoid metabolism, defense reactions, and cell death associated with the hypersensitive response of potato to incompatible races of the pathogen. ( 1) Among plant pathogens, the capacity for eicosapolyenoic acid synthesis appears to be largely restricted to oomycetes, primitive fungi (e.g., zygomycetes and chytrids), and nematodes. AA and EPA, precursors to eicosanoids that mediate inflammatory responses and serve as critical signals for immune and central nervous system functions in mammals, continue to be compelling molecules for study in plants because of what they may reveal about lipid-based signaling and induced immunity in plant-microbe interactions and possible mechanistic parallels as conserved signaling molecules across eukaryotic kingdoms. In spite of the intriguing cross-kingdom connections in AA/EPA signaling, there has been relatively little research to resolve eicosapolyenoic acid perception and action in plants, in part because of experimental limitations of systems where these fatty acids display strong activity. However, this state of affairs may change with our recent discovery that Arabidopsis responds to AA and that plants engineered to express very low levels of eicosapolyenoic acids (EP plants) have remarkably altered phenotypes to biotic challengers. 
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1559-2324
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
531-3
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Eicosapolyenoic acids: novel MAMPs with reciprocal effect on oomycete-plant defense signaling networks.
pubmed:affiliation
Department of Plant Pathology, University of California, Davis, CA, USA. rmbostock@ucdavis.edu
pubmed:publicationType
Journal Article