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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2011-9-6
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pubmed:abstractText |
Premature intra-acinar activation of trypsinogen is widely considered key for both the initiation of acute pancreatitis and the development of chronic pancreatitis. However, the biological consequences of intracellular trypsinogen activation have not been directly examined. To do so, a new mouse model was developed.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1468-3288
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1379-88
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pubmed:meshHeading |
pubmed-meshheading:21471572-Animals,
pubmed-meshheading:21471572-Enzyme Activation,
pubmed-meshheading:21471572-Gene Expression Regulation,
pubmed-meshheading:21471572-Intracellular Fluid,
pubmed-meshheading:21471572-Mice,
pubmed-meshheading:21471572-Mice, Transgenic,
pubmed-meshheading:21471572-Pancreatitis, Acute Necrotizing,
pubmed-meshheading:21471572-RNA, Messenger,
pubmed-meshheading:21471572-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:21471572-Secretory Pathway,
pubmed-meshheading:21471572-Trypsinogen
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pubmed:year |
2011
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pubmed:articleTitle |
Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis.
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pubmed:affiliation |
Department of Cancer Biology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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