21471536

Source:http://linkedlifedata.com/resource/pubmed/id/21471536

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0085983, umls-concept:C0205314, umls-concept:C0243071, umls-concept:C0280100, umls-concept:C0580822, umls-concept:C0679622, umls-concept:C1280500, umls-concept:C1547300, umls-concept:C1548760, umls-concept:C1550594
pubmed:issue	2
pubmed:dateCreated	2011-4-7
pubmed:abstractText	The antiproliferative effects of three synthetic analogs of aliphatic acetogenins selected from a previous screening were compared to those of the drugs used for the treatment of malignant pleural mesothelioma (MPM) and pancreatic ductal adenocarcinoma (PDAC).
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8806809
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Acetogenins, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-akt
pubmed:status	MEDLINE
pubmed:issn	1791-7549
pubmed:author	pubmed-author:AlecciClaudiaC, pubmed-author:FunelNiccolaN, pubmed-author:GiancolaFiorellaF, pubmed-author:GiovannettiElisaE, pubmed-author:LeónLeticia GLG, pubmed-author:PadrónJosé MJM, pubmed-author:PetersGodefridus JGJ, pubmed-author:ZucaliPaoloP
pubmed:issnType	Electronic
pubmed:volume	25
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	203-7
pubmed:meshHeading	pubmed-meshheading:21471536-Acetogenins, pubmed-meshheading:21471536-Adenocarcinoma, pubmed-meshheading:21471536-Apoptosis, pubmed-meshheading:21471536-Carcinoma, Pancreatic Ductal, pubmed-meshheading:21471536-Cell Cycle, pubmed-meshheading:21471536-Cell Line, Tumor, pubmed-meshheading:21471536-Cell Proliferation, pubmed-meshheading:21471536-Dose-Response Relationship, Drug, pubmed-meshheading:21471536-Drug Screening Assays, Antitumor, pubmed-meshheading:21471536-Enzyme-Linked Immunosorbent Assay, pubmed-meshheading:21471536-Flow Cytometry, pubmed-meshheading:21471536-Humans, pubmed-meshheading:21471536-Mesothelioma, pubmed-meshheading:21471536-Molecular Structure, pubmed-meshheading:21471536-Pancreatic Neoplasms, pubmed-meshheading:21471536-Phosphorylation, pubmed-meshheading:21471536-Pleural Neoplasms, pubmed-meshheading:21471536-Proto-Oncogene Proteins c-akt
pubmed:articleTitle	Antiproliferative effects of novel aliphatic acetogenin analogs against aggressive solid tumor cell lines.
pubmed:affiliation	BioLab, Instituto Universitario de Bio-Orgánica Antonio González (IUBO-AG), Universidad de La Laguna, C/ Astrofísico Francisco Sánchez 2, 38206 La Laguna, Spain. lgleon@ull.es
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't