Source:http://linkedlifedata.com/resource/pubmed/id/21471417
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2011-4-7
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pubmed:abstractText |
Joint instability has long been empirically recognized as a leading risk factor for osteoarthritis. However, formal mechanistic linkage of instability to osteoarthritis development has not been established. This study aimed to support a clinically accepted, but heretofore scientifically unproven, concept that the severity and rapidity of osteoarthritis development in unstable joints is dependent on the degree of instability. In a survival rabbit knee model of graded joint instability, the relationship between the magnitude of instability and the intensity of cartilage degeneration was studied at the organ level in vivo.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1535-1386
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pubmed:author | |
pubmed:copyrightInfo |
© 2011 by the Journal of Bone and Joint Surgery, Incorporated
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pubmed:issnType |
Electronic
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pubmed:day |
6
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pubmed:volume |
93
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
640-7
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pubmed:meshHeading |
pubmed-meshheading:21471417-Animals,
pubmed-meshheading:21471417-Anterior Cruciate Ligament,
pubmed-meshheading:21471417-Disease Models, Animal,
pubmed-meshheading:21471417-Disease Progression,
pubmed-meshheading:21471417-Female,
pubmed-meshheading:21471417-Joint Instability,
pubmed-meshheading:21471417-Male,
pubmed-meshheading:21471417-Osteoarthritis, Knee,
pubmed-meshheading:21471417-Rabbits,
pubmed-meshheading:21471417-Random Allocation,
pubmed-meshheading:21471417-Range of Motion, Articular,
pubmed-meshheading:21471417-Reference Values,
pubmed-meshheading:21471417-Risk Assessment,
pubmed-meshheading:21471417-Wounds and Injuries
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pubmed:year |
2011
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pubmed:articleTitle |
Instability dependency of osteoarthritis development in a rabbit model of graded anterior cruciate ligament transection.
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pubmed:affiliation |
Department of Orthopaedics and Rehabilitation, University of Iowa, Iowa City, Iowa 52242, USA. yuki-tochigi@uiowa.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, N.I.H., Extramural
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