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rdf:type |
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lifeskim:mentions |
umls-concept:C0025723,
umls-concept:C0035647,
umls-concept:C0206708,
umls-concept:C0332281,
umls-concept:C0439849,
umls-concept:C0441994,
umls-concept:C0445223,
umls-concept:C0542560,
umls-concept:C0678695,
umls-concept:C1515926,
umls-concept:C1552599,
umls-concept:C1655731,
umls-concept:C1704787,
umls-concept:C2243049,
umls-concept:C2347375
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pubmed:issue |
5
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pubmed:dateCreated |
2011-4-5
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pubmed:abstractText |
The objective of the study was to evaluate LINE-1 methylation as an intermediate biomarker for the effect of folate and vitamin B12 on the occurrence of higher grades of cervical intraepithelial neoplasia (CIN ? 2).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1873-1244
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2011 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
513-9
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:21463750-Adult,
pubmed-meshheading:21463750-Biological Markers,
pubmed-meshheading:21463750-Carbon,
pubmed-meshheading:21463750-Case-Control Studies,
pubmed-meshheading:21463750-Cervical Intraepithelial Neoplasia,
pubmed-meshheading:21463750-Cervix Uteri,
pubmed-meshheading:21463750-Confidence Intervals,
pubmed-meshheading:21463750-DNA Methylation,
pubmed-meshheading:21463750-Deoxyribonuclease I,
pubmed-meshheading:21463750-Epigenomics,
pubmed-meshheading:21463750-Female,
pubmed-meshheading:21463750-Folic Acid,
pubmed-meshheading:21463750-Follow-Up Studies,
pubmed-meshheading:21463750-Humans,
pubmed-meshheading:21463750-Leukocytes, Mononuclear,
pubmed-meshheading:21463750-Logistic Models,
pubmed-meshheading:21463750-Methylation,
pubmed-meshheading:21463750-Middle Aged,
pubmed-meshheading:21463750-Odds Ratio,
pubmed-meshheading:21463750-Papillomavirus Infections,
pubmed-meshheading:21463750-Premenopause,
pubmed-meshheading:21463750-Promoter Regions, Genetic,
pubmed-meshheading:21463750-Prospective Studies,
pubmed-meshheading:21463750-Questionnaires,
pubmed-meshheading:21463750-Risk Factors,
pubmed-meshheading:21463750-Vitamin B 12,
pubmed-meshheading:21463750-Vitamin B Complex,
pubmed-meshheading:21463750-Young Adult
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pubmed:year |
2011
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pubmed:articleTitle |
A higher degree of LINE-1 methylation in peripheral blood mononuclear cells, a one-carbon nutrient related epigenetic alteration, is associated with a lower risk of developing cervical intraepithelial neoplasia.
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pubmed:affiliation |
Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA. piyathic@uab.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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